Results 81 to 90 of about 29,746,039 (283)
International Journal of Translational MedicineBackground: Active recruitment of osteogenic cells by secreted signaling factors, such as stromal-cell-derived factor 1 (SDF-1), has recently been proposed as a novel strategy to enhance osseointegration.
Vincentius J. Suhardi +4 more
doaj +1 more source
SDF-1/CXCL12: A Chemokine in the Life Cycle of HIV [PDF]
Frontiers in Immunology, 2015 Since 1986, the beginning of our involvement in HIV research, our major interest was focused on the regulation of HIV-1 replication by the transcriptional host cell machinery. Thus, we successively investigated the consequences of inflammatory and specific responses in HIV replication in primary monocytes and memory CD4 + T cells, and explored with ...
openaire +3 more sources
SDF-1α-PPADT nanoparticles promote the repair of electrical burn vascular injury in rats.
, 2018 (A) Hematoxylin and eosin staining of muscle and vascular tissues. Vascular morphology of the 6 s electrical burn group injected with SDF-1α-PPADT nanoparticles is relatively intact. Endothelial cells are better organized and continuous (arrow).
Guo-Sheng Wu (477657) +11 more
core +1 more source
Advanced Science, EarlyView.ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Platelets, 2017 Platelet surface expression levels of stromal cell derived factor 1 (SDF-1) are elevated in acute coronary syndrome and associated with LVEF% improvement after myocardial infarction (MI).
Dominik Rath +10 more
doaj +1 more source
PLoS ONE, 2013 We have demonstrated that blocking CXCR4 may be a potent anti-metastatic therapy for CXCR4-related oral cancer. However, as CXCR4 antagonists are currently in clinical use to induce the mobilization of hematopoietic stem cells, continuous administration ...
Nobuyuki Kuribayashi +6 more
doaj +1 more source
SDF-1α-induced Akt phosphorylation at Thr308 and Ser473 and Akt-dependent platelet aggregation.
, 2017 (A) Washed human platelets were treated with 500 ng/ml SDF-1α for 10 min at 37°C. Resting platelets (left lane) and SDF-1α-treated platelets (right lane) were lysed in the Laemmli sample buffer containing phosphatase inhibitors and separated by SDS-PAGE.
Kohji Kasahara (3628436) +10 more
core +1 more source
SDF-1α/CXCR4 Signaling in Lipid Rafts Induces Platelet Aggregation via PI3 Kinase-Dependent Akt Phosphorylation. [PDF]
, 2017 Stromal cell-derived factor-1α (SDF-1α)-induced platelet aggregation is mediated through its G protein-coupled receptor CXCR4 and phosphatidylinositol 3 kinase (PI3K).
Morio Arai +21 more
core +1 more source
Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure
Advanced Science, EarlyView.Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye +6 more
wiley +1 more source