Results 131 to 140 of about 29,746,039 (283)
Phytotherapy Research, EarlyView.ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong +7 more
wiley +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Obesity is a major risk factor for type 2 diabetes. Some traditional Chinese medicine (TCM) compounds can improve obesity by increasing energy consumption. This study aimed to identify and verify TCM compounds that promote adipose thermogenesis to alleviate obesity via transcriptomic analysis, molecular docking, network pharmacology, and ...
Jing Li +6 more
wiley +1 more source
, 2014 (A) On day -5, hemizygous K14 VEGF-A transgenic mice (n = 14) were sensitized with 2% oxazolone and challenged on day 0 with 1% oxazolone on the ears. Starting 7 days after challenge, mice received i.v injections of anti-SDF-1 antibody or isotype-matched
Katrin Kerl (389982) +3 more
core +1 more source
Phytotherapy Research, EarlyView.Chaetocin induces ferroptosis in cisplatin‐resistant ovarian cancer cells through neddylation‐mediated TFRC upregulation. ABSTRACT Ovarian cancer (OV) is a highly lethal gynecological tumor, often developing platinum chemotherapy resistance and treatment failure.
Hanfei Xie +5 more
wiley +1 more source
, 2012 Size exclusion chromatography using a Superdex-75 column for SDF-1/CXCL12 produced by a combination of dilution and dialysis refolding technique (A) and a combination of reverse-dilution and dialysis refolding technique (B).
Yingping Zhuang (131817) +7 more
core +1 more source
School Board Elections in England and Wales, 1870–1902: An Electoral Experiment?
History, EarlyView.Abstract The 1870 Elementary Education Act enabled the creation of school boards in England and Wales. Members were directly elected by the cumulative vote. This method gave each individual voter as many votes as there were seats on a school board, in some cases up to fifteen.
ED GREEN
wiley +1 more source
The dual crisis: Climate change simultaneously drives pollinator decline and pest outbreaks
Agricultural and Forest Entomology, EarlyView.Climate change acts as an asymmetric ecological filter, favouring r‐selected pest traits (rapid reproduction, generalism) while disadvantaging K‐selected pollinators. For every 1°C of warming, bee species richness declines ~25% since the 1990s, while pest‐induced crop losses increase by 10%–25%. A network‐centric approach integrating climate‐responsive
Diriba Fufa Serdo
wiley +1 more source
SDF-1/CXCR4 pathway controls actin cytoskeleton.
, 2012 A: Treatment with SDF-1 increased the actin filament density in primary chondrocytes. Primary chondrocytes from wild-type mice were treated with SDF-1 (100 ng/ml), or SDF-1 and CXCR4 specific antagonist, TF14016 (100 µM) or pertussis toxin (PTX, 100 ng ...
Nobutaka Fujii (164590) +12 more
core +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
Andrology, EarlyView.ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Selecting high‐quality spermatozoa with optimal nuclear integrity is a crucial step in assisted reproductive technologies (ART). While density gradient centrifugation (DGC) is widely used, the associated centrifugation steps may induce cell stress, potentially damaging sperm DNA.
Simone Palini +7 more
wiley +1 more source