Results 171 to 180 of about 27,322,199 (337)
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto +12 more
wiley +1 more source
Polimorfismi a Singolo Nucleotide e Cellule Progenitrici Endoteliali [PDF]
Uno dei più interessanti target della ricerca clinica in campo cardiovascolare degli ultimi anni è rappresentato dalle Cellule Progenitrici Endoteliali (EPC).
ROVAI, GAIA
core
Chemotherapy‐induced WNT ligand secretion by bone marrow (BM) stroma drives acute lymphoblastic leukaemia (ALL) chemoresistance. WNT pathway inhibition disrupts this cross‐talk and restores therapeutic response, highlighting WNT inhibitors as a promising strategy to prevent relapse in ALL.
Foteini Kalampalika +4 more
wiley +1 more source
Fostamatinib had 46% durable response, with 73% steroid reduction, in this multicentre retrospective study of refractory wAIHA/ES. Hypertension, gastrointestinal (GI) distress and neutropenia occurred in 23%. Only one patient required drug discontinuation and one patient dose reduction.
Jorge N. Ruiz Lopez +16 more
wiley +1 more source
血清SDF-1联合CXCL5及CEA联合检测用于乳腺癌诊断的敏感度与特异性分析
目的探究并分析血清SDF-1(基质细胞衍生因子-1)联合CXCL5(外周血趋化因子-5)及CEA(癌胚抗原)联合检测用于乳腺癌诊断的敏感度与特异性。方法选取2015年6月-2016年6月收治的50例乳腺癌患者,50例乳腺良性肿瘤患者及50名正常志愿者,分别作为乳腺癌组、乳腺良性肿瘤组及对照组。测定各组患者血清SDF-1、CXCL5及CEA浓度,采用血清SDF-1、CXCL5、CEA及SDF-1+CXCL5作为诊断指标对所有受试者进行诊断,比较上述诊断方法的准确性(包括敏感性、特异性及一致性 ...
安雪青, 吕健东, 苏锋, 赵建勋
doaj
Summary Immune thrombocytopenia (ITP) is a complex autoimmune disorder characterized by accelerated destruction of peripheral platelets and impaired megakaryopoiesis. While the cellular effectors, dysregulated T cells, hyperactive B cells and phagocytic macrophages are well characterized, the upstream epigenetic mechanisms orchestrating this ...
Zhenyu Liu +8 more
wiley +1 more source
Mesenchymal Stem Cells Enhanced Metastasis of Neuroblastoma Via SDF-1/CXCR4 and SDF-1/CXCR7 Signalling [PDF]
Ma, M., Chan, G.C.-F.
openaire +1 more source
The role of 67 kDa laminin receptor in G-CSF-induced hematopoietic stem cell mobilization [PDF]
Visconte, Valeria
core +1 more source
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu +9 more
wiley +1 more source

