Results 161 to 170 of about 27,322,199 (337)

A stromal cell-derived factor-1 releasing matrix enhances the progenitor cell response and blood vessel growth in ischaemic skeletal muscle [PDF]

European Cells & Materials, 2011
Although many regenerative cell therapies are being developed to replace or regenerate ischaemic muscle, the lack of vasculature and poor persistence of the therapeutic cells represent major limiting factors to successful tissue restoration.
D Kuraitis, P Zhang, Y Zhang, DT Padavan, K McEwan, T Sofrenovic, D McKee, J Zhang, M Griffith, X Cao, A Musarò, M Ruel, EJ Suuronen   +12 more
doaj  

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Activation of CXCR7 exerts an inhibitory effect on adipogenesis through regulation of β-arrestin2/Wnt and AKT signalling

Adipocyte
CXCR7, an alternative receptor for the inflammatory chemokine SDF-1, is involved in cell proliferation and migration. Recent studies have reported that CXCR7 also plays a role in adipose tissue.
Shiyue Sun, Muhammad Arif Aslam, Eun Bi Ma, Gahui Lee, Hafiz Muhammad Ahmad Javaid, Somy Yoon, Joo Young Huh   +6 more
doaj   +1 more source

Current Trends and Future Prospects of Integrating Electrospinning With 3D Printing Techniques for Mimicking Bone Extracellular Matrix Scaffolds

Journal of Polymer Science, Volume 63, Issue 6, Page 1481-1504, 15 March 2025.
ABSTRACT This article presents a review of the recent findings on the combination of electrospun nanofibers and three‐dimensional (3D)‐printed structures for extracellular matrix (ECM) scaffolds for bone tissue engineering. We explore the synergy between electrospinning (ES), which produces highly porous, fibrous structures from materials like collagen
Kardo Khalid Abdullah, Kolos Molnár
wiley   +1 more source

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Qing Ma, Daniel M Jones, P. Borghesani, R. Segal, T. Nagasawa, T. Kishimoto, R. Bronson, T. Springer   +7 more
semanticscholar   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Serum stromal cell-derived factor-1 concentrations are increased and associated with nonalcoholic fatty liver disease in children with obesity

BMC Endocrine Disorders
Introduction Stromal cell-derived factor-1 (SDF-1) is a newly discovered small molecule adipocytokine, and research has shown that it is closely related to the occurrence and development of obesity.
Yuesheng Liu, Lijun Hao, Linhao Wang, Mengnan Lu, Chunyan Yin, Yanfeng Xiao   +5 more
doaj   +1 more source

Effect of silver diamine fluoride on nicotine-induced Streptococcus mutans biofilmWhy Is This Important?

JADA Foundational Science
Background: Silver diamine fluoride (SDF) reagent is used to prevent and arrest caries lesions. However, the mechanism of its action is not fully reported.
Marwa M. Elsharkasi, BDS, MSD, ABOD, George J. Eckert, MAS, Richard L. Gregory, PhD   +2 more
doaj   +1 more source

Fertilization influences overyielding through dominance of species with high specific leaf area in young tree mixtures

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract In the context of anthropogenic eutrophication of the biosphere, understanding the impact of nutrient addition on plant diversity–productivity relationships remains a major challenge.
Dai F. Saito, Friderike Beyer, Grégoire T. Freschet, Anja Klingler, Charles A. Nock, Peter B. Reich, Michael Scherer‐Lorenzen, Jürgen Bauhus   +7 more
wiley   +1 more source

School Board Elections in England and Wales, 1870–1902: An Electoral Experiment?

History, EarlyView.
Abstract The 1870 Elementary Education Act enabled the creation of school boards in England and Wales. Members were directly elected by the cumulative vote. This method gave each individual voter as many votes as there were seats on a school board, in some cases up to fifteen.
ED GREEN
wiley   +1 more source