Results 1 to 10 of about 711 (175)

Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells.

PLoS ONE, 2019
Succinate dehydrogenase (SDH) inhibitors (SDHIs) are used worldwide to limit the proliferation of molds on plants and plant products. However, as SDH, also known as respiratory chain (RC) complex II, is a universal component of mitochondria from living ...
Paule Bénit, Agathe Kahn, Dominique Chretien, Sylvie Bortoli, Laurence Huc, Manuel Schiff, Anne-Paule Gimenez-Roqueplo, Judith Favier, Pierre Gressens, Malgorzata Rak, Pierre Rustin   +10 more
doaj   +8 more sources

Inhibition of Succinate Dehydrogenase by Pesticides (SDHIs) and Energy Metabolism. [PDF]

Int J Mol Sci, 2023
Succinate dehydrogenase (SDH) is one of the enzymes of the tricarboxylic acid cycle (Krebs cycle) and complex II of the mitochondrial respiratory chain. A class of fungicides (SDHIs) targets the complex II reaction in the SDH. A large number of those in use have been shown to inhibit SDH in other phyla, including humans.
Bouillaud F.
europepmc   +5 more sources

Exploring Fungicide Sensitivity in Soybean Stem Blight Pathogen Diaporthe longicolla, Emphasizing Genetic Variability Impact on Response to SDHI Fungicides Fluopyram and Pydiflumetofen [PDF]

Journal of Fungi
Diaporthe species are critical plant pathogens that contribute to a disease complex responsible for substantial yield losses in soybean production worldwide.
Shanshan Chen, Zhanyun Liu, Zhengjie Chang, Yuxin Zheng, Xueyang Wang, Ningwei Li, Zhongqiao Huang, Can Zhang, Xili Liu   +8 more
doaj   +4 more sources

Shifting sensitivity of septoria tritici blotch compromises field performance and yield of main fungicides in Europe [PDF]

Frontiers in Plant Science, 2022
Septoria tritici blotch (STB; Zymoseptoria tritici) is a severe leaf disease on wheat in Northern Europe. Fungicide resistance in the populations of Z. tritici is increasingly challenging future control options.
Lise Nistrup Jørgensen, Niels Matzen, Thies Marten Heick, Aoife O’Driscoll, Bill Clark, Katherine Waite, Jonathan Blake, Mariola Glazek, Claude Maumene, Gilles Couleaud, Bernd Rodemann, Stephan Weigand, Charlotte Bataille, Bán R, Pierre Hellin, Steven Kildea, Gerd Stammler   +16 more
doaj   +2 more sources

Double Mutations in Succinate Dehydrogenase Are Involved in SDHI Resistance in Corynespora cassiicola [PDF]

Microorganisms, 2022
With the further application of succinate dehydrogenase inhibitors (SDHI), the resistance caused by double mutations in target gene is gradually becoming a serious problem, leading to a decrease of control efficacy. It is important to assess the sensitivity and fitness of double mutations to SDHI in Corynespora cassiicola and analysis the evolution of ...
Bingxue Sun, Guangxue Zhu, Xuewen Xie, Ali Chai, Lei Li, Yanxia Shi, Baoju Li   +6 more
openalex   +5 more sources

Impact of Exposure to Pyraclostrobin and to a Pyraclostrobin/Boscalid Mixture on the Mitochondrial Function of Human Hepatocytes [PDF]

Molecules, 2023
Fungicides are widely used in agriculture for crop protection. Succinate dehydrogenase inhibitors (SDHIs) and strobilurins inhibit mitochondria electron transport chain (ETC) in fungi, by blocking complex II and complex III, respectively.
Mélina Carbone, Barbara Mathieu, Yasmine Vandensande, Bernard Gallez   +3 more
doaj   +2 more sources

Activity of the Novel Succinate Dehydrogenase Inhibitor Fungicide Pydiflumetofen Against SDHI-Sensitive and SDHI-Resistant Isolates of Botrytis cinerea and Efficacy Against Gray Mold [PDF]

Plant Disease, 2020
Succinate dehydrogenase inhibitor (SDHI) fungicides are currently the most frequently used fungicides for controlling gray mold. However, isolates of Botrytis cinerea resistant to SDHI fungicides have emerged in the field. Pydiflumetofen is a new SDHI fungicide that can control a variety of fungal diseases, but its efficacy against gray mold and ...
Leiming He, Kaidi Cui, Yufei Song, Tongtong Li, Ning Liu, Wei Mu, Feng Liu   +6 more
openalex   +3 more sources

The Short-Term Exposure to SDHI Fungicides Boscalid and Bixafen Induces a Mitochondrial Dysfunction in Selective Human Cell Lines [PDF]

Molecules, 2021
Fungicides are used to suppress the growth of fungi for crop protection. The most widely used fungicides are succinate dehydrogenase inhibitors (SDHIs) that act by blocking succinate dehydrogenase, the complex II of the mitochondrial electron transport ...
Donatienne d’Hose, Pauline Isenborghs, Davide Brusa, Bénédicte F. Jordan, Bernard Gallez   +4 more
doaj   +2 more sources

Detection of sdhB gene mutations in SDHI-resistant isolates of Botrytis cinerea using high resolution melting (HRM) analysis [PDF]

Frontiers in Microbiology, 2016
Botrytis cinerea, is a high-risk pathogen for fungicide resistance development. Pathogen` resistance to SDHIs is associated with several mutations in sdh gene.
Anastasios Samaras, Panagiotis Madesis, George Karaoglanidis   +2 more
doaj   +2 more sources

Resistance of Black Aspergilli Species from Grape Vineyards to SDHI, QoI, DMI, and Phenylpyrrole Fungicides [PDF]

Journal of Fungi, 2023
Fungicide applications constitute a management practice that reduces the size of fungal populations and by acting as a genetic drift factor, may affect pathogen evolution.
Stefanos I. Testempasis, George S. Karaoglanidis   +1 more
doaj   +2 more sources