Results 111 to 120 of about 4,922,643 (264)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
SDS-PAGE and Western blot analysis of expressed 8mer-peptides.
, 2019 (a, c, e, g, i) SDS-PAGE analysis of expressed 8mer-peptides. It indicates each 8mer-peptide for numbers P57-P65 of P1, P68-P74 of P17, P75-P83 of 21, P84-P92 of P25, P93-P109 of P29 and P30, P110-P117 of P31, P118-P126 of P41 and P127-P135 of P48.
Yijie Li (653857) +11 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Mljekarstvo, 2013 The aim of this work was to investigate primary proteolysis of white brined goat cheese prepared from raw milk and to correlate with the results obtained with high-molarity Tris buffer electrophoretic system.
Milenko Smiljanić +5 more
doaj
AlgorithmsSodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) is used to identify protein presence, absence, or overexpression and usually, their interpretation is visual.
Jorge Juarez-Lucero +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
A taxonomical study on electrophoretic pattern of blood serum protein of some fish of karakaya dam lake [PDF]
Eurasian Journal of Veterinary SciencesIn this study, an electrophoretic comparison of serum blood proteins of two species of fish, Capoeta trutta and Capoeia capoeta umbla, were carried out. Study was carried between june and october in 1997. Using the Random Sampling Method, 92 C.
Muhittin Yılmaz +4 more
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
SDS-PAGE analysis of the proteins from T. spiralis muscle larvae.
, 2018 The images indicated that several different proteins (arrow) were identified via 12% SDS-PAGE.
Xiaodi Yang (469303) +8 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source