Results 121 to 130 of about 4,922,643 (264)
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doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Functional evaluation of complement factor I variants by immunoassays and SDS-PAGE. [PDF]
Gerogianni A +7 more
europepmc +1 more source
SDS-PAGE assay of RvEis and MsEis proteins.
Equal amount of boiled and unboiled RvEis and MsEis proteins were electrophoresed on 8% SDS-PAGE gel. Lane 1- boiled RvEis, lane 2- unboiled RvEis, lane 3- boiled MsEis and lane 4- unboiled MsEis. H- Hexamer, T- Trimers and M- Monomers. Markers are shown
Shashi Anand (6504245) +2 more
core +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
SDS-PAGE electrophoretic migration pattern of the H. volcanii S-layer protein.
SDS-PAGE electrophoretic migration pattern of the H. volcanii S-layer protein.
Bernhard Schuster (6690011) +5 more
core +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
A total of 65 identified isolates of coliform bacteria Salmonella, including Campylobacter and Staphylococcus isolated from different control points of a poultry slaughterhouse in Ankara, Turkey were characterized by morphological, biochemical and ...
Ayhan Temiz +4 more
doaj
Germplasm characterization and SDS-PAGE analysis of caper (Capparis spinosa L.) from different provenances. [PDF]
Wang M, Yuan X, Xu L.
europepmc +1 more source

