Results 61 to 70 of about 41,193 (292)

Membrane-permeabilized sonodynamic therapy enhances drug delivery into macrophages.

open access: yesPLoS ONE, 2019
Macrophages play a pivotal role in the formation and development of atherosclerosis as a predominant inflammatory cell type present within atherosclerotic plaque.
Zhengyu Cao   +9 more
doaj   +1 more source

Development and optimisation of in vitro sonodynamic therapy for glioblastoma

open access: yesScientific Reports, 2023
Sonodynamic therapy (SDT) is currently on critical path for glioblastoma therapeutics. SDT is a non-invasive approach utilising focused ultrasound to activate photosensitisers like 5-ALA to impede tumour growth.
Andrew Keenlyside   +13 more
doaj   +1 more source

Decision noise: An explanation for observed violations of signal detection theory [PDF]

open access: yes, 2008
In signal detection theory (SDT), responses are governed by perceptual noise and\ud a flexible decision criterion. Recent criticisms of SDT (see, eg, Balakrishnan, 1999) have\ud identified violations of its assumptions, and researchers have suggested ...
Mueller, S.T.   +2 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng   +10 more
wiley   +1 more source

Self Determination Theory (SDT): a review on SDT as a Complementary Theory of Motivation

open access: yesKelaniya Journal of Human Resource Management, 2016
Self Determination theory is a comprehensive theory of motivation of human behavior supporting that humans are naturally growth oriented and seek out relationships, connections and challenges that aid humanistic growth and develop their authentic self.
openaire   +2 more sources

Diabetic Retinal and Choroidal Edema in SDT Rats [PDF]

open access: yes, 2016
We evaluated the features of diabetic retinal and choroidal edema in Spontaneously Diabetic Torii (SDT) rats. We measured the retinal and choroidal thicknesses in normal Sprague-Dawley (SD) rats (n=9) and SDT rats (n=8). The eyes were enucleated 40 weeks
Akihiro Kakehashi   +5 more
core   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

open access: yesAdvanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu   +11 more
wiley   +1 more source

Effect of Sipjeondaebo-Tang on the Pharmacokinetics of S-1, an Anticancer Agent, in Rats Evaluated by Population Pharmacokinetic Modeling

open access: yesMolecules, 2017
S-1 (TS-1®) is an oral fluoropyrimidine anticancer agent containing tegafur, oteracil, and gimeracil. Sipjeondaebo-tang (SDT) is a traditional oriental herbal medicine that has potential to alleviate chemotherapy-related adverse effects.
Tae Hwan Kim   +11 more
doaj   +1 more source

Time Resolved DNA Barcodes for Information Encoding and Dynamic Encryption

open access: yesAdvanced Science, EarlyView.
This study establishes a molecular information platform based on DNA Temporal Barcodes. Information is encoded through combinations of DNA tags with distinct retention times, while dynamic encryption is achieved through a key‐triggered DNA ligation.
Likang Chu   +7 more
wiley   +1 more source

PINK1/Parkin-Mediated Mitophagy Promotes Resistance to Sonodynamic Therapy

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Sonodynamic therapy (SDT), based on the synergistic effect of low-intensity ultrasound and sonosensitizer, is a potential approach for non-invasive treatment of cancers.
Lin Song   +7 more
doaj   +1 more source

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