Results 111 to 120 of about 24,482,269 (284)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Elementary status of patients with type 2 diabetes depending on the duration of the disease, age and sex

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Essential elements play an important role in the pathophysiology of diabetes mellitus and its complications. The study of their level in the body of patients provides an opportunity to clarify various mechanisms of pathological deviations and
V.I. Kravchenko, L.K. Sokolova, K.Yu. Ivaskiv, O.V. Rakov, Ya.B. Kulchynska, M.D. Tronko   +5 more
doaj   +1 more source

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, EarlyView.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source

Analysis of the elemental composition in blood serum and hair of adolescents of different ethnic groups in Khabarovsk krai in connection with nutrition and technogenic contamination of territories

Сеченовский вестник, 2018
An ecological and biological examination of adolescents of the following ethnic groups of Khabarovsk Krai was conducted: Nivkhs (n = 25), Evens (n = 54) and newly arrived Russians (n = 23), whose average age amounted to 14.57 ± 0.24, 14.6 ± 0.2 and 15.00
A. O. Nesterenk, E. D. Tselykh, N. K. Khristoforova, N. V. Berdnikov   +3 more
doaj  

Os opostos, se não se atraem, se complementam

Revista Discente Ofícios de Clio
A longa revolução francesa é um dos temas sobre os quais os que lidam com passado mais se debruçaram e produziram, entre esses estão Alexis de Tocqueville e Karl Marx. No presente artigo, apresentarei a conjuntura dessa revolução sobre a qual tratam os autores.
openaire   +1 more source

ESG Performance and Credit Risk: Evidence From Chinese Manufacturing Companies

International Journal of Finance &Economics, EarlyView.
ABSTRACT This study investigates the effect of corporate environmental, social, and governance (ESG) performance on credit risk using a sample of manufacturing firms listed on China's Shanghai and Shenzhen A‐share markets from 2009 to 2021. Employing fixed effects, the generalised method of moments, and instrumental variable models, we find that ...
Yanan Wang, Xiao Zhang, Michal Wojewodzki, Yuxin Jian, Fadey AbiDaoud   +4 more
wiley   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

La vénériculture : ses acquis, ses contraintes, ses problèmes [PDF]

, 1989
L'élevage contrôlé de l'adulte reproducteur à l'adulte consommable, ou vénériculture, est l'aboutissement de recherches publiques et privées. Inconnu en 1980, cet élevage est en 1988 en phase de production, dynamisé par une nouvelle profession qui, dans bien des cas jusqu'en 1987, est issue d ...
openaire  

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source

Navigating ESG in the Artificial Intelligence Era: Evidence From AI Pilot Zones in China

International Studies of Economics, EarlyView.
ABSTRACT Artificial intelligence is reshaping business models, but limited literature explores how ESG evolves in the AI era. This paper regards AI Pilot Zones in China as a quasi‐natural experiment, and adopts the DID approach to investigate its impact on corporate ESG performance. Using the sample of Chinese A‐share listed companies from 2016 to 2022,
Yujie Liu, Xinyi Shen
wiley   +1 more source