Head &Neck, EarlyView.ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun +11 more
wiley +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
Hesperetin loaded fucoidan selenium nanoparticles alleviate cisplatin induced acute kidney injury via antioxidant and cGAS STING pathway regulation. [PDF]
Discov NanoLong L, Zhang Y, Xiao J, Zang J.
europepmc +1 more source
Total Neoadjuvant Treatment for Esophageal Adenocarcinoma With Oligometastases: TNT‐OES‐1 Trial
International Journal of Cancer, EarlyView.Total neoadjuvant therapy could combine the potentially strong systemic effect of FLOT chemotherapy with the good locoregional control of CROSS chemoradiotherapy. While total neoadjuvant therapy is increasingly used in rectal cancer, its potential in gastroesophageal cancer remains largely unexplored.
Charlène J. van der Zijden +12 more
wiley +1 more source
Gradient Built-In Electric Field Engineering in Hierarchical Co<sub>0.85</sub>Se Quantum Dots-Modified Cadmium Sulfide Nanorods for Boosted Photocatalytic H<sub>2</sub> Evolution. [PDF]
ChemSusChemZhu X +7 more
europepmc +1 more source
How Does AI Empower Corporate ESG Practices? Mechanisms Based on Information Processing Theory
International Journal of Finance &Economics, EarlyView.ABSTRACT In the context of the latest technological revolution and industrial transformation, Artificial Intelligence (AI) provides new impetus for the development of corporate ESG practices. This study, based on data from 2630 A‐share listed companies in China from 2010 to 2022, examines the impact of AI on corporate ESG performance and its mechanisms
Qin Zhu, Shanshan Jiang, Anna Min Du
wiley +1 more source
Neuroprotective potential of synthesized coumarin-based glycinate and heterocyclic amide derivatives: an acetylcholinesterase inhibition study. [PDF]
Sci RepFarag B +6 more
europepmc +1 more source
Trade Measures—Relationships and Implications
International Journal of Finance &Economics, EarlyView.ABSTRACT Various value‐added trade measures have been developed to address the concern in the growing volume of trade in intermediates that are double counted when crossing international borders more than once. This paper raises a query and makes an inquiry into the query.
Peijie Wang, Zhiyuan Liu
wiley +1 more source
[Transforming vaccination brigades with an offline digital app: evidence from the Peruvian Amazon, 2025Transformando as brigadas de vacinação por meio de um aplicativo digital sem conexão com a internet: evidências da Amazônia peruana, 2025]. [PDF]
Rev Panam Salud PublicaQuepuy-Izarra MDR +11 more
europepmc +1 more source