Results 31 to 40 of about 25,164,155 (279)

Kant on de se [PDF]

open access: yes, 2018
Since the classic works by Castañeda, Perry and Lewis, de se thoughts have been described as thoughts about oneself ‘as oneself’. In recent years, various theoretical perspectives have gained ground, and even if the transcendental system does not seem to
Forgione, Luca
core   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin   +11 more
wiley   +1 more source

Fundamental in vitro 3D human skin equivalent tool development for assessing biological safety and biocompatibility – towards alternative for animal experiments

open access: yes4 open, 2021
Nowadays, human skin constructs (HSCs) are required for biomaterials, pharmaceuticals and cosmetics in vitro testing and for the development of complex skin wound therapeutics.
Idrees Ayesha   +9 more
doaj   +1 more source

Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice [PDF]

open access: yes, 2008
Many tumor antigens have been identified that can be targeted by the immune system. Animal models that have been genetically modified to express human HLA molecules instead of their own MHC antigens have shown to be valuable in the discovery of peptides ...
McArdle, SE
core  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Differential Object Marking, Case and Agreement

open access: yesBorealis: An International Journal of Hispanic Linguistics, 2013
In this paper, we present empirical evidence showing that Differential Object Marking (DOM)  in Spanish is determined by structural conditions related to Case and agreement. We also argue that semantic concepts such as specificity, definiteness, animacy,
Javier Ormazabal, Juan Romero
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

Engaging with clinicians to implement and evaluate the ICF in neurorehabilitation practice [PDF]

open access: yes, 2015
INTRODUCTION: Although deemed a globally accepted framework, there remains scare evidence on the process and outcome of implementing the International Classification of Functioning, Disability and Health (ICF) within neurorehabilitation. OBJECTIVES: This
Jefferson, R, Tempest, SE
core   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández   +10 more
wiley   +1 more source

Ocular biometric parameters in South-Indian children with myopia – A hospital-based retrospective descriptive analysis

open access: yesIndian Journal of Ophthalmology
Aim: This study aims to profile the ocular biometric parameters in a large group of children of South-Indian ethnicity who visited our outpatient children’s department and were diagnosed with myopia. Methods: Children
Sandra Ganesh   +6 more
doaj   +1 more source

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