Results 81 to 90 of about 24,482,269 (284)

Differential Object Marking in Spanish: state of the art

open access: yesBorealis: An International Journal of Hispanic Linguistics, 2013
This state of the art tries to cover as much as possible about the properties, conditions and analyses of Differential Object Marking (DOM) in Spanish.
Antonio Fábregas
doaj   +1 more source

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

Antecedents of Patient Loyalty: Exploring Mediating and Moderating Paradigms in Public Hospitals

open access: yesPatient Preference and Adherence
Abid Hussain,1 Shahida Kanwel,2 Sania Khan,3 Wadi B Alonazi,4 Azam Malik,3 Ali Ahmed Khan5 1School of Nursing, Shandong Xiehe University, Jinan, 250109, People’s Republic of China; 2School of Management, Jiangsu University, Zhenjiang, Jiangsu, 212013 ...
Hussain A   +5 more
doaj  

Homogenization in strength and durability analysis of reinforced tooth filling [PDF]

open access: yes, 2002
An asymptotic homogenization procedure is employed to obtain effective elastic properties of the composite tooth filling, a homogenized macro– stress field and a first approximation to the micro-stress field, from properties of the components and applied
Mikhailov, SE, Orlik, J
core  

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić   +7 more
wiley   +1 more source

Content of micro- and macroelements in patients with autoimmune thyroiditis and subclinical hypothyroidism

open access: yesPatologìâ
Aim. To investigate the content of iodine (I), selenium (Se), zinc (Zn), magnesium (Mg), calcium (Ca) and vitamin D, the thyroid volume and thyroid functional state in patients with autoimmune thyroiditis (AIT) and subclinical hypothyroidism (SCH), to ...
V. I. Kravchenko   +4 more
doaj   +1 more source

Quasi-static stationary-periodic model of percussive deep drilling [PDF]

open access: yes, 2005
Copyright @ 2005 Patron EditoreIn the percussively deep drilling, the rock is modeled by an infinite elastic medium with a semi-infinite cylindrical bore-hole having a curvilinear bottom.
Mikhailov, SE, Namestnikova, IV
core  

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh   +5 more
wiley   +1 more source

Fatigue strength and durability analysis by normalised equivalent stress functionals [PDF]

open access: yes, 2003
Generalised fatigue durability diagrams are considered for a material under multi-axial loading given by a (non-regularly) oscillating function of time.
Mikhailov, SE, Namestnikova, IV
core   +1 more source

Integrated Reporting in the Public Sector: Theoretical Foundations and Determinants of Quality

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Integrated reporting (IR) has gained attention as the IFRS Foundation promotes its use through the International Integrated Reporting Council framework (IIRF). Public sector (PS) organizations, as key drivers of economic, social and environmental sustainability, are increasingly adopting IR to enhance transparency and accountability.
Ana Zorio‐Grima, Andreea Hancu‐Budui
wiley   +1 more source

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