Results 91 to 100 of about 13,240,439 (301)
Barriers to adaptation to sea-level rise [PDF]
, 2013 Increasingly there is recognition from researchers and policy makers that there are legal, institutional and cultural barriers to climate change adaptation that will need to be addressed if we are able to adapt efficiently and equitably.
Elissa Waters +2 more
core
Stakeholder preferences and perceived effectiveness of coastal adaptation measures in Seychelles
npj Climate ActionEffective coastal adaptation to sea-level rise (SLR) is a complex and urgent challenge, especially for Small Island Developing States (SIDS), where responses are shaped by social, ecological, and governance dynamics. Here, we investigate how stakeholders
Jesper Weishaupt +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Sea-level rise and impacts projections under a future scenario with large greenhouse gas emission reductions [PDF]
, 2011 Using projections from two coupled climate models (HadCM3C and HadGEM2-AO), we consider the effect on 21st century sea-level rise (SLR) of mitigation policies relative to a scenario of business-as-usual (BAU).
R. J. Nicholls +9 more
core +1 more source
ECONOMY-WIDE ESTIMATES OF THE IMPLICATIONS OF CLIMATE CHANGE: SEA LEVEL RISE [PDF]
The economy-wide implications of sea level rise in 2050 are estimated using a static computable general equilibrium model. Overall, general equilibrium effects increase the costs of sea level rise, but not necessarily in every sector or region.
Richard S.J. Tol +2 more
core +2 more sources
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
SEA LEVEL RISE AND EQUITY WEIGHTING [PDF]
Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of national socio-economic scenarios.
Richard S.J. Tol +2 more
core
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source