Results 101 to 110 of about 13,240,439 (301)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
A Global Perspective on Local Sea Level Changes
Journal of Marine Science and EngineeringIn 2021, the IPCC published new sea level projections. For the first time, the projections gave insight into expected relative sea level rise locally.
Hessel G. Voortman, Rob De Vos
doaj +1 more source
Estimating global mean sea-level rise and its uncertainties by 2100 and 2300 from an expert survey
npj Climate and Atmospheric Science, 2020 Sea-level rise projections and knowledge of their uncertainties are vital to make informed mitigation and adaptation decisions. To elicit projections from members of the scientific community regarding future global mean sea-level (GMSL) rise, we repeated
B. Horton +8 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
The Economic Impact of Substantial Sea-Level Rise [PDF]
Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of socio-economic scenarios downscaled to the national level, including the four SRES storylines.
Richard S.J. Tol +3 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Hourly delayed mode sea level from coastal tide gauge station Gibraltar in 1977
, 2006 Hourly sea level from coastal tide gauge station Eastport in 1963 (Research quality ...
WOCE Sea Level, WSL +1 more
core +1 more source
State Agency Sea-Level Rise Action Plan for California [PDF]
, 2022 Numerous state agencies are dedicated to helping California prepare for sea-level rise (SLR). Our vision is to make all of California, including its coastlines, inland areas, and bays and estuaries, resilient to the impacts of SLR, such as flooding ...
Sea-Level Rise Leadership Team +1 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source