Results 121 to 130 of about 2,443,175 (254)
Quaternary sediment patterns in the Weddell Sea: relations and environmental conditions [PDF]
, 1988 Sediment patterns such as texture, composition, and facies from three selected areas of the Antarctic continental margin of the Weddell Sea are discussed in relation to environmental variations of the Quaternary hydrosphere and kryosphere.
Fütterer, Dieter +2 more
core +1 more source
Extreme Conditions in the Bering Sea (2017–2018): Record‐Breaking Low Sea‐Ice Extent
Geophysical Research Letters, 2019 The lowest winter‐maximum areal sea‐ice coverage on record (1980–2019) in the Bering Sea occurred in the winter of 2017/2018. Sea ice arrived late due to warm southerly winds in November. More typical northerly winds (albeit warm) in December and January
P. Stabeno, S. Bell
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Version 2 of the EUMETSAT OSI SAF and ESA CCI sea-ice concentration climate data records
The Cryosphere, 2018 . We introduce the OSI-450, the SICCI-25km and the SICCI-50km climate data records of gridded global sea-ice concentration. These three records are derived from passive microwave satellite data and offer three distinct advantages compared to existing ...
T. Lavergne +16 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Scientific Reports, 2019 Sea ice is an important transport vehicle for gaseous, dissolved and particulate matter in the Arctic Ocean. Due to the recently observed acceleration in sea ice drift, it has been assumed that more matter is advected by the Transpolar Drift from shallow
T. Krumpen +11 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Satellite SAR Data-based Sea Ice Classification: An Overview
Géosciences, 2019 A review of the main approaches developed for sea ice classification using satellite imagery is presented. Satellite data are the main and very often only information source for sea ice classification and charting in the remote arctic regions.
N. Zakhvatkina, V. Smirnov, I. Bychkova
semanticscholar +1 more source
Molecular Oncology, EarlyView.In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella +18 more
wiley +1 more source
GNSS transpolar earth reflectometry exploriNg system (G-TERN): mission concept [PDF]
, 2018 The global navigation satellite system (GNSS) Transpolar Earth Reflectometry exploriNg system (G-TERN) was proposed in response to ESA's Earth Explorer 9 revised call by a team of 33 multi-disciplinary scientists.
Baggen, Rens +4 more
core +2 more sources