Results 91 to 100 of about 283,051 (325)

Improving passive microwave sea ice concentration algorithms for coastal areas: applications to the Baltic Sea

open access: yes, 2010
Sea ice concentration can be retrieved from passive microwave data using the NASA Team algorithm or the Artist Sea Ice (ASI) algorithm, for example.
Kaleschke, L., Maass, N.
core   +1 more source

The Effect of Changing Sea Ice on the Vulnerability of Arctic Coasts [PDF]

open access: yes, 2014
Shorefast sea ice prevents the interaction of the land and the ocean in the Arctic winter and influences this interaction in the summer by governing the fetch.
Anderson, R S   +2 more
core   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Seasonal to interannual Arctic sea-ice predictability in current GCMs [PDF]

open access: yes, 2014
We establish the first inter-model comparison of seasonal to interannual predictability of present-day Arctic climate by performing coordinated sets of idealized ensemble predictions with four state-of-the-art global climate models.
Balmaseda   +32 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Investigation of North Pacific sea ice anomalies in the context of atmospheric and oceanic variability [PDF]

open access: yes, 2001
Thesis (M.S.) University of Alaska Fairbanks, 2001This study investigates the main mode of variability in North Pacific sea ice and examines the relationship between sea ice concentration and northern hemispheric climate variability for the period 1968 ...
Tivy, Adrienne
core  

The atmospheric impact of uncertainties in recent Arctic Sea ice reconstructions [PDF]

open access: yes, 2005
There are significant discrepancies between observational datasets of Arctic sea ice concentrations covering the last three decades, which result in differences of over 20% in Arctic summer sea ice extent/area and 5%–10% in winter.
Bamber, J.L.   +2 more
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Towards Sea Ice Remote Sensing with Space Detected GPS Signals: Demonstration of Technical Feasibility and Initial Consistency Check Using Low Resolution Sea Ice Information

open access: yesRemote Sensing, 2010
This paper presents two space detected Global Positioning System (GPS)signals reflected off sea ice and compares the returned power profiles with independent estimates of ice concentration provided by the Advanced Microwave Scanning Radiometer (AMSR-E ...
Scott Gleason
doaj   +1 more source

The interpretation of spikes and trends in concentration of nitrate in polar ice cores, based on evidence from snow and atmospheric measurements [PDF]

open access: yes, 2008
Nitrate is frequently measured in ice cores, but its interpretation remains immature. Using daily snow surface concentrations of nitrate at Halley (Antarctica) for 2004 - 2005, we show that sharp spikes (> factor 2) in nitrate concentration can occur ...
Bauguitte, S.J.-B.   +3 more
core   +3 more sources

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