Results 91 to 100 of about 288,973 (326)

Investigation of North Pacific sea ice anomalies in the context of atmospheric and oceanic variability [PDF]

, 2001
Thesis (M.S.) University of Alaska Fairbanks, 2001This study investigates the main mode of variability in North Pacific sea ice and examines the relationship between sea ice concentration and northern hemispheric climate variability for the period 1968 ...
Tivy, Adrienne
core  

Anomalous peak in Antarctic sea-ice area, winter 1998, coincident with ENSO [PDF]

, 2001
The results of an updated satellite analysis of hemispheric and regional Antarctic sea-ice cover are presented based on October 1987-September I999 Special Sensor Microwave/Imager (SSM/I) data.
Bell, Bjørgo, Bromwich, Cavalieri, Comiso, De la Mare, Edward Hanna, Federov, Hanna, Hanna, Hanna, Johannessen, Parkinson, Simmons, Slingo, Smith, Stammerjohn, Timmermann, Urban, Van den Broeke, Vinnikov, Watkins, White, Wu, Yuan   +24 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Sea-ice evaluation of NEMO-Nordic 1.0: a NEMO–LIM3.6-based ocean–sea-ice model setup for the North Sea and Baltic Sea [PDF]

Geoscientific Model Development, 2017
The Baltic Sea is a seasonally ice-covered marginal sea in northern Europe with intense wintertime ship traffic and a sensitive ecosystem. Understanding and modeling the evolution of the sea-ice pack is important for climate effect studies and ...
P. Pemberton, U. Löptien, R. Hordoir, A. Höglund, S. Schimanke, L. Axell, J. Haapala   +6 more
doaj   +1 more source

Improving passive microwave sea ice concentration algorithms for coastal areas: applications to the Baltic Sea

, 2010
Sea ice concentration can be retrieved from passive microwave data using the NASA Team algorithm or the Artist Sea Ice (ASI) algorithm, for example.
Kaleschke, L., Maass, N.
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Arctic Ocean sea ice response to Northern Annular Mode-like wind forcing [PDF]

, 2003
The response of the Arctic Ocean sea ice system to Northern Annular Mode-like wind forcing has been investigated using an ocean/sea ice general circulation model coupled to an atmospheric boundary layer model.
Krahmann, Gerd, Visbeck, Martin
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

The atmospheric impact of uncertainties in recent Arctic Sea ice reconstructions [PDF]

, 2005
There are significant discrepancies between observational datasets of Arctic sea ice concentrations covering the last three decades, which result in differences of over 20% in Arctic summer sea ice extent/area and 5%–10% in winter.
Bamber, J.L., Singarayer, J.S., Valdes, P.J.   +2 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source