Results 81 to 90 of about 40,901 (260)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Sea ice concentration decline in an important Adélie penguin molt area. [PDF]
Proc Natl Acad Sci U S A, 2023 Schmidt AE +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
AI4SeaIce: selecting loss functions for automated SAR sea ice concentration charting. [PDF]
Sci Rep, 2023 Kucik A, Stokholm A.
europepmc +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Author Correction: AI4SeaIce: selecting loss functions for automated SAR sea ice concentration charting. [PDF]
Sci Rep, 2023 Kucik A, Stokholm A.
europepmc +1 more source
Study of Antarctic Sea Ice Based on Shipborne Camera Images and Deep Learning Method
Remote SensingSea ice parameters are crucial for polar ship design. During China’s 39th Antarctic Scientific Expedition, ice condition from the entire navigation process of the research vessel Xuelong 2 was recorded using shipborne cameras.
Xiaodong Chen +4 more
doaj +1 more source
An ensemble reconstruction of global monthly sea surface temperature and sea ice concentration 1000-1849. [PDF]
Sci Data, 2021 Samakinwa E +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source