Results 81 to 90 of about 294,753 (307)

Sea ice inertial oscillations in the Arctic Basin [PDF]

, 2012
International audienceAn original method to quantify the amplitude of inertial motion of oceanic and ice drifters, through the introduction of a non-dimensional parameter M defined from a spectral analysis, is presented.
Barnier, Bernard, Gimbert, Florent, Jourdain, Nicolas C., Marsan, David, Weiss, Jérôme   +4 more
core   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Improved simulation of Antarctic sea ice due to the radiative effects of falling snow [PDF]

, 2017
Southern Ocean sea-ice cover exerts critical control on local albedo and Antarctic precipitation, but simulated Antarctic sea-ice concentration commonly disagrees with observations.
Boucher O, Eric Fetzer, Graeme Stephens, Holland M M, IPCC ed Stocker T F, J-L F Li, Jia-Yuh Yu, Mark Richardson, Neale R B, Rhein M, Wei-Liang Lee, Yi-Hui Wang, Yinghui Liu, Yulan Hong   +13 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Optimising assimilation of sea ice concentration in an Earth system model with a multicategory sea ice model [PDF]

Tellus A: Dynamic Meteorology and Oceanography, 2018
A data assimilation method capable of constraining the sea ice of an Earth system model in a dynamically consistent manner has the potential to enhance the accuracy of climate reconstructions and predictions. Finding such a method is challenging because the sea ice dynamics is highly non-linear, and sea ice variables are strongly non-Gaussian ...
Kimmritz, M., Counillon, F., Bitz, C.M., Massonnet, François, Bethke, I., Gao, Y.   +5 more
openaire   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Sea-ice evaluation of NEMO-Nordic 1.0: a NEMO–LIM3.6-based ocean–sea-ice model setup for the North Sea and Baltic Sea [PDF]

Geoscientific Model Development, 2017
The Baltic Sea is a seasonally ice-covered marginal sea in northern Europe with intense wintertime ship traffic and a sensitive ecosystem. Understanding and modeling the evolution of the sea-ice pack is important for climate effect studies and ...
P. Pemberton, U. Löptien, R. Hordoir, A. Höglund, S. Schimanke, L. Axell, J. Haapala   +6 more
doaj   +1 more source

Anomalous peak in Antarctic sea-ice area, winter 1998, coincident with ENSO [PDF]

, 1976
The results of an updated satellite analysis of hemispheric and regional Antarctic sea-ice cover are presented based on October 1987-September I999 Special Sensor Microwave/Imager (SSM/I) data.
Edward Hanna, Bell, Bjørgo, Bromwich, Cavalieri, Comiso, De la Mare, Federov, Hanna, Hanna, Hanna, Johannessen, Parkinson, Simmons, Slingo, Smith, Stammerjohn, Timmermann, Urban, Van den Broeke, Vinnikov, Watkins, White, Wu, Yuan   +24 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Improvement of Arctic Sea Ice Type Concentration Retrieval From Microwave Remote Sensing Data

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sea ice types, such as first-year ice and multiyear ice, can be discriminated based on radiometric and scattering signatures. However, changes in ice surface properties caused by processes like ice surface deformation and melt-refreeze events can lead to
Yanbing Luo, Yufang Ye, Yawen Huang, Mohammed Shokr, Zhuoqi Chen, Xiao Cheng   +5 more
doaj   +1 more source