Results 101 to 110 of about 38,499 (290)
Assessment of Arctic sea ice simulations in cGENIE model and projections under RCP scenarios
Scientific ReportsSimulating and predicting Arctic sea ice accurately remains an academic focus due to the complex and unclear mechanisms of Arctic sea ice variability and model biases.
Di Chen, Min Fu, Xin Liu, Qizhen Sun
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Coastal ice-core record of recent northwest Greenland temperature and sea-ice concentration [PDF]
, 2015 E. C. Osterberg +5 more
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Sea Ice Concentration Manifestation in Radar Signal at Low Incidence Angles Depending on Wind Speed
Remote SensingIn previous studies, the possibilities of Ku-band radar measurements at low incidence angles were investigated for the task of sea ice detection. In this paper, the sensitivity of normalized radar cross-section to sea ice concentration is investigated at
Maria Panfilova, Vladimir Karaev
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
The scale of the whale: using video-tag data to evaluate sea-surface ice concentration from the perspective of individual Antarctic minke whales [PDF]
, 2020 Jacob M. J. Linsky +5 more
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ERA-40 SST and Sea Ice Concentration Data [PDF]
, 2001 The lower boundary condition of sea surface temperature (SST) and sea-ice concentration (sic) is a critical forcing of the lower frequencies in multi-decadal global atmospheric reanalyses such as ERA-40. Partly in response to the ERA-40 project, new SST/sic data sets have been developed that are considerably improved over those available to the first ...
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Advancing Arctic Sea Ice Remote Sensing with AI and Deep Learning: Opportunities and Challenges
Remote SensingRevolutionary advances in artificial intelligence (AI) in the past decade have brought transformative innovation across science and engineering disciplines.
Wenwen Li, Chia-Yu Hsu, Marco Tedesco
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