Results 101 to 110 of about 288,973 (326)

Seasonal to interannual Arctic sea-ice predictability in current GCMs [PDF]

open access: yes, 2014
We establish the first inter-model comparison of seasonal to interannual predictability of present-day Arctic climate by performing coordinated sets of idealized ensemble predictions with four state-of-the-art global climate models.
Balmaseda   +32 more
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Laboratory study on coprecipitation of phosphate with ikaite in sea ice [PDF]

open access: yes, 2014
Ikaite (CaCO3 6H2O) has recently been discovered in sea ice, providing first direct evidence of CaCO3 precipitation in sea ice. However, the impact of ikaite precipitation on phosphate (PO4) concentration has not been considered so far.
Dieckmann, Gerhard S.   +3 more
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Towards Sea Ice Remote Sensing with Space Detected GPS Signals: Demonstration of Technical Feasibility and Initial Consistency Check Using Low Resolution Sea Ice Information

open access: yesRemote Sensing, 2010
This paper presents two space detected Global Positioning System (GPS)signals reflected off sea ice and compares the returned power profiles with independent estimates of ice concentration provided by the Advanced Microwave Scanning Radiometer (AMSR-E ...
Scott Gleason
doaj   +1 more source

The interpretation of spikes and trends in concentration of nitrate in polar ice cores, based on evidence from snow and atmospheric measurements [PDF]

open access: yes, 2008
Nitrate is frequently measured in ice cores, but its interpretation remains immature. Using daily snow surface concentrations of nitrate at Halley (Antarctica) for 2004 - 2005, we show that sharp spikes (> factor 2) in nitrate concentration can occur ...
Bauguitte, S.J.-B.   +3 more
core   +3 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Temporal dynamics of ikaite in experimental sea ice [PDF]

open access: yes, 2014
Ikaite (CaCO3 · 6H2O) is a metastable phase of calcium carbonate that normally forms in a cold environment and/or under high pressure. Recently, ikaite crystals have been found in sea ice, and it has been suggested that their precipitation may play an ...
Campbell, K.   +14 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Spatial cross-correlation of Antarctic Sea ice and seabed topography [PDF]

open access: yes
A time series of derived sea ice concentrations as observed about Antarctica by the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) satellite in 1983 is considered.
Deveaux, Richard D., Phelan, Michael J.
core   +1 more source

Home - About - Disclaimer - Privacy