Results 101 to 110 of about 283,051 (325)
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Abnormal Winter Melting of the Arctic Sea Ice Cap Observed by the Spaceborne Passive Microwave Sensors [PDF]
Journal of Astronomy and Space Sciences, 2016 The spatial size and variation of Arctic sea ice play an important role in Earth’s climate system. These are affected by conditions in the polar atmosphere and Arctic sea temperatures.
Seongsuk Lee, Yu Yi
doaj +1 more source
A Long-Term and Reproducible Passive Microwave Sea Ice Concentration Data Record for Climate Studies and Monitoring [PDF]
, 2013 A long-term, consistent, and reproducible satellite-based passive microwave sea ice concentration climate data record (CDR) is available for climate studies, monitoring, and model validation with an initial operation capability (IOC).
Meier, W. N. +3 more
core +3 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Temporal dynamics of ikaite in experimental sea ice [PDF]
, 2014 Ikaite (CaCO3 · 6H2O) is a metastable phase of calcium carbonate that normally forms in a cold environment and/or under high pressure. Recently, ikaite crystals have been found in sea ice, and it has been suggested that their precipitation may play an ...
Campbell, K. +14 more
core +2 more sources
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Spatial cross-correlation of Antarctic Sea ice and seabed topography [PDF]
A time series of derived sea ice concentrations as observed about Antarctica by the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) satellite in 1983 is considered.
Deveaux, Richard D., Phelan, Michael J.
core +1 more source
Arctic Ocean sea ice response to Northern Annular Mode-like wind forcing [PDF]
, 2003 The response of the Arctic Ocean sea ice system to Northern Annular Mode-like wind forcing has been investigated using an ocean/sea ice general circulation model coupled to an atmospheric boundary layer model.
Krahmann, Gerd, Visbeck, Martin
core +1 more source
Molecular Oncology, EarlyView.We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová +14 more
wiley +1 more source