Results 121 to 130 of about 288,973 (326)

Sea ice concentration decline in an important Adélie penguin molt area. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Schmidt AE   +6 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Report of the first Nimbus-7 SMMR Experiment Team Workshop [PDF]

open access: yes
Preliminary results of sea ice and techniques for calculating sea ice concentration and multiyear fraction from the microwave radiances obtained from the Nimbus-7 SMMR were presented. From these results, it is evident that these groups used different and
Campbell, W. J., Gloersen, P.
core   +1 more source

Under-ice phytoplankton blooms inhibited by spring convective mixing in refreezing leads [PDF]

open access: yes, 2018
Author Posting. © American Geophysical Union, 2018. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution.
Arrigo, Kevin R.   +11 more
core   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

AARI methodology for sea ice charts composition

open access: yesРоссийская Арктика, 2019
Sea ice charts of the Arctic and Antarctic Research Institute (AARI) are widely used nowadays for a variety of scientific and practical tasks. However, detailed description of ice charts composition still has not been published.
E.V. Afanasyeva   +6 more
doaj   +1 more source

EOF analysis of three records of sea-ice concentration spanning the last 30 years [PDF]

open access: yes, 2003
Several continuous observational datasets of Artic sea-ice concentration are currently available that cover the period since the advent of routine satellite observations. We report on a comparison of three sea-ice concentration datasets.
Comiso   +8 more
core   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause   +6 more
wiley   +1 more source

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