Results 71 to 80 of about 108,237 (301)

ECONOMY-WIDE ESTIMATES OF THE IMPLICATIONS OF CLIMATE CHANGE: SEA LEVEL RISE [PDF]

The economy-wide implications of sea level rise in 2050 are estimated using a static computable general equilibrium model. Overall, general equilibrium effects increase the costs of sea level rise, but not necessarily in every sector or region.
Richard S.J. Tol, Francesco Bosello, Roberto Roson   +2 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Sea-level rise scenarios.

, 2021
Recent historic and projected rates of sea-level rise for San Francisco Bay. The observed change in annual mean sea level (mm yr-1) from 1981–2015 at the Golden Gate gage, relative to 2000 (bold line) and projected rates of sea-level rise from four ...
Lisa M. Schile-Beers (11586714), John C. Callaway (11586711), Kevin J. Buffington (11586702), Bruce D. Dugger (11586708), Christopher N. Janousek (11586705), Evyan Borgnis Sloane (11586717), Karen M. Thorne (9607176)   +6 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

SEA LEVEL RISE AND EQUITY WEIGHTING [PDF]

Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of national socio-economic scenarios.
Richard S.J. Tol, Robert J. Nicholls, David Anthoff   +2 more
core  

Twentieth-Century Global-Mean Sea Level Rise: Is the Whole Greater than the Sum of the Parts? [PDF]

, 2012
Confidence in projections of global-mean sea level rise (GMSLR) depends on an ability to account for GMSLR during the twentieth century. There are contributions from ocean thermal expansion, mass loss from glaciers and ice sheets, groundwater extraction,
Wada, Y., Fettweis, Xavier, Tamisiea, M. E., Tamisiea, Mark, White, Neil, Church, J. A., Huybrechts, Philippe, Wada, Yoshihide, Box, J.E., Tamisiea, M.E., Marzeion, B., Wake, L. M., Gregory, Jonathan, Church, J.A., Konikow, L., Bierkens, M.F.P., Church, John, Oerlemans, Johannes, Cogley, J.G., Oerlemans, J., van den Broeke, M., Marzeion, Ben, Box, J., Leclercq, P., Gregory, J.M., Leclercq, P.W., Bierkens, Marc, van de Wal, R., Leclercq, P. W., van de Wal, R.S.W., van den Broeke, M R., Cogley, J., Wake, L.M., Broeke, M.R. van den, White, N. J., Box, Jason, Hanna, Edward, Cogley, Graham, Fettweis, X., Bierkens, M. F. P., Van den Broeke, M. R., Van de Wal, R. S. W., Konikow, Leonard, Wake, Leanne, Gregory, J., Konikow, L. F., White, N., Cogley, J. G., Leclercq, Paul, van de Wal, Roderik, Gregory, Jonathan M., Wake, L., Church, J., Huybrechts, P., Tamisiea, M., Bierkens, M., Konikow, L.F., Hanna, E., White, N.J., Tamisiea, E., Box, J. E., van den Broeke, Michiel   +61 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The Economic Impact of Substantial Sea-Level Rise [PDF]

Using the FUND model, an impact assessment is conducted over the 21st century for rises in sea level of up to 2-m/century and a range of socio-economic scenarios downscaled to the national level, including the four SRES storylines.
Richard S.J. Tol, Edgar L.W. Morgenroth, Robert J. Nicholls, David Anthoff   +3 more
core