Results 71 to 80 of about 11,361,096 (291)

Learning About Sea Level Rise Uncertainty Improves Coastal Adaptation Decisions

open access: yesEarth's Future
Adaptive decision‐making allows decision‐makers to plan long‐term coastal infrastructure under uncertain sea level rise projections. To date, economic assessments of adaptive decision‐making that take into account future learning about sea level rise ...
Vanessa Völz   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

High Performance Computing-enabled Sea-Level Rise Hazard Analysis

open access: yes, 2023
Sea level rise, as a result of climate change, is expected to drive coastal hazards that bring significant damages to coastal communities in the future. There are mainly three factors that contribute to the global sea level rise: ocean thermal expansion,
Luo, Xiao
core  

Adaptation to multi-meter sea-level rise should start now

open access: yes, 2023
International audienceSea-level rise will fundamentally change coastal zones worldwide (Cooley et al 2022). A global two meters rise of sea level will be exceeded sooner or later within a time window ranging from one century to as long as two millennia ...
Cozannet, Gonéri, Le   +5 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Vulnerability, Impacts, and Adaptation to Sea Level Rise: Taking an Ecosystem-Based Approach [PDF]

open access: yesOceanography, 2012
Last year I traveled to Bangkok, Thailand, for the second Asia Pacific Adaptation Forum, which was called off at the last minute due to the city's worst flooding in the past 50 years. Bangkok, an urban center of great wealth in a relatively rich country,
Keith Alverson
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Barriers to adaptation to sea-level rise [PDF]

open access: yes, 2013
Increasingly there is recognition from researchers and policy makers that there are legal, institutional and cultural barriers to climate change adaptation that will need to be addressed if we are able to adapt efficiently and equitably.
Elissa Waters   +2 more
core  

Stakeholder preferences and perceived effectiveness of coastal adaptation measures in Seychelles

open access: yesnpj Climate Action
Effective coastal adaptation to sea-level rise (SLR) is a complex and urgent challenge, especially for Small Island Developing States (SIDS), where responses are shaped by social, ecological, and governance dynamics. Here, we investigate how stakeholders
Jesper Weishaupt   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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