Results 121 to 130 of about 6,117,121 (293)

Sea surface salinity Hovmoller

, 2016
Sea surface salinity Hovmöller diagram generated from a FOAM reanalysis (http://www.metoffice.gov.uk/research/models/ocean ...
Matthew Martin (3368342)
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

LETKF‐based Ocean Research Analysis (LORA) version 1.0

Geoscience Data Journal
Local ensemble transform Kalman filter (LETKF)‐based Ocean Research Analysis (LORA) version 1.0 datasets for western North Pacific (WNP) and Maritime Continent (MC) regions (LORA‐WNP and ‐MC, respectively) are released through the JAXA‐RIKEN Ocean ...
Shun Ohishi, Takemasa Miyoshi, Takafusa Ando, Tomohiko Higashiuwatoko, Eri Yoshizawa, Hiroshi Murakami, Misako Kachi   +6 more
doaj   +1 more source

Measurements of sea surface temperature and salinity in a large seawater basin under varying precipitation intensities and droplet characteristics

We provide data from experiments with artificial rain over a 5100-liter basin with a retractable roof, where temperature and conductivity (to calculate salinity) were measured at different depths in the upper sea surface, as well as rain properties ...
Ribas-Ribas, Mariana, Esters, Leonie, Wurl, Oliver, Gassen, Lisa   +3 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Thin Sea Ice Thickness Prediction Using Multivariate Radar-Physical Features and Machine Learning Algorithms

Remote Sensing
Climate change in the Arctic is causing significant declines in sea ice extent and thickness. This study investigated lab-grownsea ice thickness using Linear Regression and three Machine Learning algorithms: Decision Tree, Random Forest, and Fully ...
Mehran Dadjoo, Dustin Isleifson
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Sea surface salinity of sediment core GeoB5844-2

, 2003
Sea surface salinity of sediment core GeoB5844-
Jürgen Pätzold (6962099), Peter J Müller (6959537), Moammar, Mustafa O, Pätzold, Jürgen, Helge W Arz (6958289), Müller, Peter J, Arz, Helge Wolfgang, Mustafa O Moammar (6982412)   +7 more
core   +1 more source

Electrochemical Behavior of Flame‐Sprayed Sc‐Doped AlCoCrFeMo High‐Entropy Alloy Coatings in 3.5% Sodium Chloride Solution

Advanced Engineering Materials, EarlyView.
Scandium (Sc)‐doped AlCoCrFeMo HEA coatings are fabricated via flame spraying with 0.1, 0.3, and 0.5 wt% Sc additions. Among these, the HEA‐Sc0.3 coating exhibits the highest corrosion resistance, indicated by a more positive corrosion potential and lower current density.
Pankaj Kumar, Akash Vyas, Mohammad Aatif Qazi, Nashit Jalal, Maria Ophelia Jarligo, Mostafa Yakout, Jing Liu, André McDonald   +7 more
wiley   +1 more source