Results 101 to 110 of about 6,117,121 (293)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Three hundred eighty thousand year long stable isotope and faunal records from the Red Sea : influence of global sea level change on hydrography [PDF]

, 1996
Stable isotope and faunal records from the central Red Sea show high-amplitude oscillations for the past 380,000 years. Positive δ18O anomalies indicate periods of significant salt buildup during periods of lowered sea level when water mass exchange with
Christoph Hemleben, Erlenkeuser, Helmut, Dieter Meischner, Helmut Erlenkeuser, Birgit Hiller, Hemleben, Christoph, Meischner, Dieter, Zahn, Rainer, Ahuva Almogi‐Labin, Almogi-Labin, Ahuva, Hiller, Birgit, Rainer Zahn   +11 more
core   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

RRS "Discovery" Cruise D279, 04 Apr - 10 May 2004. A Transatlantic hydrography section at 24.5N [PDF]

, 2005
The cruise report describes the acquisition and processing of transatlantic hydrographic, velocity, chemistry and other measurements made during three cruises in Spring 2004 at 24.5°N.
Cunningham, S.A.
core   +1 more source

Monitoring Sea Surface Temperature and Sea Surface Salinity Around the Maltese Islands Using Sentinel-2 Imagery and the Random Forest Algorithm

Applied Sciences
Marine regions are undergoing rapid evolution, primarily driven by natural and anthropogenic activities. Safeguarding these ecosystems necessitates the ability to observe their physical features and control processes with precision in both space and time.
Gareth Craig Darmanin, Adam Gauci, Monica Giona Bucci, Alan Deidun   +3 more
doaj   +1 more source

Remote Sensing Observations of the Winter Yellow Sea Warm Current Invasion into the Bohai Sea, China

Advances in Meteorology, 2016
Using ASCAT, QuikSCAT, and MODIS data, we analyzed the sea surface wind field, temperature, salinity, and chlorophyll concentrations in the mixed zone between the Bohai Sea and Yellow Sea in the winter (the period of winter 2013 included December 2013 ...
Jie Guo, Hua Zhang, Tingwei Cui, Yijun He, Jie Zhang, Kai Guo, Chawei Hou, Rongjie Liu   +7 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Southern Ocean anthropogenic carbon sink constrained by sea surface salinity. [PDF]

Sci Adv, 2021
Terhaar J, Frölicher TL, Joos F.
europepmc   +1 more source

From the Allerød to the mid-Holocene: Palynological evidence from the south basin of the Caspian Sea [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which
López-Merino, L, Chalié, F., López-Merino, Lourdes, Lopez-Merino, L., Leroy, S.A.G., Gasse, F, Tudryn, A, Chalié, Françoise, Gasse, Françoise, Tudryn, A., Gasse, F., Leroy, Suzanne A.G., Chalié, F, Tudryn, Alina   +13 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source