Results 61 to 70 of about 6,117,121 (293)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Meteorological and sea surface water measurement data from Icebreaker Research Vessel ARAON for 2010-2019 Arctic research expeditions [PDF]
Geo Data, 2019 Despite of its economic and scientific significances with mineral resources, the Northern Sea Routes, and climate change, the Arctic Ocean has been a challenge for long-term continuous environmental observations.
Dongseob Shin +3 more
doaj +1 more source
Sea surface temperatures of the western Arabian Sea during the last deglaciation. [PDF]
, 2007 In this study we present a sea surface temperature (SST) record from the western Arabian Sea for the last 20,000 years. We produced centennial-scale d18O and Mg/Ca SST time series of core NIOP929 with focus on the glacial-interglacial transition.
H. Elderfield +14 more
core +2 more sources
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Journal of Marine Science and EngineeringThe lack of dimensionality of ocean observations makes it difficult to utilize multi-scale data assimilation to correct model errors with limited observations.
Yueqi Zhao, Zhongjie He, Yuhang Jiang
doaj +1 more source
Changing Salinity Gradients in the Baltic Sea As a Consequence of Altered Freshwater Budgets
Geophysical Research Letters, 2019 Climate change is expected to enhance the hydrological cycle in northern latitudes reducing the salinity in the Baltic Sea, a land‐locked marginal sea with a large catchment area located in northern Europe.
Madline Kniebusch +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Scientia Marina, 2011 We study the interannual and seasonal variability in the Mediterranean Sea over the period 1958-2004 by comparing a numerical simulation (the 1/4º ORCA-R025 G70 model run, ‘ORCA’ hereafter) with altimetry and the MEDAR temperature and salinity database ...
Enrique Vidal-Vijande +4 more
doaj +1 more source
Evaporation induced convection enhances mixing in the upper ocean
Frontiers in Marine Science, 2023 The upper ocean surface layer is directly affected by the air-sea fluxes. The diurnal variations in these fluxes also cause the upper ocean mixed layer turbulence and mixing to diurnally vary. The underlying thermohaline structure also varies accordingly
Devang Falor +5 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source