Results 121 to 130 of about 802,355 (333)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Determination of sea surface temperatures from microwave and IR data [PDF]

Microwave measurements from the Nimbus 7 SMMR were used to derive the atmospheric precipitable water, which was then used to obtain the atmospheric correction for use with AVHRR thermal IR measurements to obtain sea surface temperature (SST).
Grover, J., Rangaswamy, S.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A 94/183 GHz multichannel radiometer for Convair flights [PDF]

A multichannel 94/183 GHz radiometer was designed, built, and installed on the NASA Convair 990 research aircraft to take data for hurricane penetration flights, SEASAT-A underflights for measuring rain and water vapor, and Nimbus-G underflights for new ...
Forsythe, R. E., Gagliano, J. A., Schuchardt, J. M., Stratigos, J. A.   +3 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

EUMETSAT Sea Surface Temperature activities

, 2018
Presentation given at the 20th GHRSST science meeting (XX), ESA/ESRIN, Frascati, Italy, June 3 - 7, 2019.
openaire   +1 more source

Solar signals in sea level pressure and sea surface temperature

, 2010
We investigate solar cycle signals in 150 years of Sea Level Pressure (SLP) and Sea Surface Temperature (SST) data, using multiple regression analysis. We detect a solar signal in both SLP and SST in the North Pacific during DJF, similar to that found by Van Loon et al. (2007) but of smaller magnitude. We do not, however, identify the signal they found
Roy, Indrani, Roy, Indrani
openaire   +4 more sources

Surface temperatures and temperature gradient features of the US Gulf Coast waters [PDF]

Satellite thermal infrared data on the Gulf of Mexico show that a seasonal cycle exists in the horizontal surface temperature structure. In the fall, the surface temperatures of both coastal and deep waters are nearly uniform.
Huh, O. K., Rouse, L. J., Jr., Smith, G. W.   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Observational case study revealing oceanic internal solitary waves modulating air-sea interactions in northern South China sea

Scientific Reports
Internal solitary waves (ISWs) are extreme oceanic dynamic processes that significantly modulate sea surface currents and roughness, but their roles in air-sea interactions are still poorly understood.
Zeyu Chang, Xiaodong Huang, Wei Zhao, Zhiwei Zhang, Lei Guan, Chun Zhou, Jiwei Tian   +6 more
doaj   +1 more source