Results 101 to 110 of about 9,437,769 (262)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Sea surface temperature reconstruction for ODP Site 145-882

, 2016
Sea surface temperature reconstruction for ODP Site 145 ...
Yamamoto, Masanobu, Masanobu Yamamoto (6968687), Kobayashi, Daisuke, Daisuke Kobayashi (448930)   +3 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Seasonal Variability of Wind, Surface Current and Sea Surface Temperature in the Eastern Seram Waters During the 2015 Super El Nino

Nekton
The eastern Seram waters are influenced by both the Seram Sea and the Banda Sea. This study aimed to examine variations in wind, surface currents, and sea surface temperature (SST) during 2015, coinciding with the super El Niño event.
Cipta Utama, Simon Tubalawony, Harold Joppie Davido Waas, Ronald Darlly Hukubun, Marlin Chrisye Wattimena   +4 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Alkenones and reconstructed sea surface temperature from sediment core MD9-963

, 1997
Alkenones and reconstructed sea surface temperature from sediment core MD9 ...
Luc Beaufort (6961133), Bard, Edouard, Corinne Sonzogni (2446018), Luc Beaufort, Ganssen, Gerald M, Gerald M Ganssen (7044224), Rostek, Frauke, Édouard Bard (6976076), Corinne Sonzogni, Beaufort, Luc, Frauke Rostek, Sonzogni, Corinne, Edouard Bard, Frauke Rostek (7835132), Gerald Ganssen   +14 more
core   +1 more source

Remotly Sensed Sea Surface Temperature from Aircraft

Gayana, 2004
The experiment was conducted around south of the Azores islands, in the middle eastern part of the northern-Atlantic basin. The experimental area was situated between 31°N-38°N and 21°W-28°W. The experiment was performed in order to improve our knowledge
B. H. Kwon, B. Benech, P. Durand, Y. S. Kim   +3 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Page 1 SOME REMARKS ON MECHANISMS FOR THE REGULATION OF TROPICAL

, 2008
It hardly needs elaboration that the regulation of tropical sea surface temperature is a central problem in climate, with repercussions ranging from the paleoclimatic domain (e.g. climate of the last glacial maximum vs.
R. T. Pierrehumbert, Sea Surface Temperature   +1 more
core