Results 81 to 90 of about 9,437,769 (262)

The Relationships Between Meridional Position of North Pacific Sea Surface Temperature Anomalies and North American Surface Temperatures Revealed by CMIP6 Models

Geophysical Research Letters, 2023
In this study, we obtained the first leading mode and principal component 1 (PC1) of North Pacific sea surface temperature (SST). The PC1‐related SST anomalies, located relatively north/south, are referred to as North/South PC1 events.
Tao Wang, Xiaohua Gou, Wenshou Tian, Xuejia Wang, Fei Xie   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Sea surface temperature and sea ice indicators on sediment core PS2089-2

, 2002
Sea surface temperature and sea ice indicators on sediment core PS2089-
Rainer Gersonde (6961220), Gersonde, Rainer, Kunz-Pirrung, Martina, David A Hodell (6959735), Hodell, David A, Martina Kunz-Pirrung (7890827)   +5 more
core   +1 more source

Uncertainty estimates in regional and global observed temperature changes: A new data set from 1850 [PDF]

, 2006
The historical surface temperature data set HadCRUT provides a record of surface temperature trends and variability since 1850. A new version of this data set, HadCRUT3, has been produced, benefiting from recent improvements to the sea surface ...
P. Brohan, Jones, P. D., Harris, I., Tett, Simon F. B., P. D. Jones, Kennedy, John J., Kennedy, J. J., Harris, Ian, Brohan, P., Tett, S. F. B., I. Harris, Brohan, Philip, Jones, Philip D., S. F. B. Tett, J. J. Kennedy   +14 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

(Table 1) Sea surface temperature reconstruction for sediment surface samples

, 2000
(Table 1) Sea surface temperature reconstruction for sediment surface ...
Erlenkeuser, Helmut, Francisca C Martinez-Ruiz (6966821), Ulrich Struck (6973964), Sakamoto, Tatsuhiko, Emeis, Kay-Christian, Mark Rosenberg (6982664), Struck, Ulrich, Bernasconi, Stefano M, Martinez-Ruiz, Francisca C, Tatsuhiko Sakamoto (6966824), Rosenberg, Mark, Hans-Martin Schulz (6982661), Stefano M Bernasconi (6967457), Helmut Erlenkeuser (7886135), Schulz, Hans-Martin, Kay-Christian Emeis (6958973)   +15 more
core   +1 more source

ANALISIS HUBUNGAN PRODUKSI PERIKANAN TANGKAP LAUT, CURAH HUJAN, DAN SUHU PERMUKAAN LAUT DENGAN MODEL VECTOR AUTOREGRESSIVE (VAR)

E-Jurnal Matematika, 2019
NTT Province is one of the provinces with the largest marine catch fisheries production in Indonesia. Rainfall and sea surface temperature are factors that affect marine catch fisheries production.
RAMADHAN LENGGU RAMLI, I WAYAN SUMARJAYA, KARTIKA SARI   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Sea surface temperature reconstruction for sediment core MD97-2146

, 2016
Sea surface temperature reconstruction for sediment core MD97 ...
Shintani, Tomoya, Yamamoto, Masanobu, Tomoya Shintani (7062167), Masanobu Yamamoto (6968687), Min-Te Chen (6960200), Chen, Min-Te   +5 more
core   +1 more source

Global analysis of night marine air temperature and its uncertainty since 1880: the HadNMAT2 Dataset [PDF]

, 2013
An updated version of the Met Office Hadley Centre’s monthly night marine air temperature dataset is presented. It is available on a 5? latitude-longitude grid from 1880 as anomalies relative to 1961-1990 calendar-monthly climatological average night ...
Berry, D.I., Moat, B.I., Nick A. Rayner, Bengamin I. Moat, John J. Kennedy, Michael Saunby, Elizabeth C. Kent, Parker, D.E., Kennedy, J.J., Rayner, N.A., David E. Parker, Kent, E.C., David I. Berry, Saunby, M.   +13 more
core   +1 more source