Results 121 to 130 of about 9,437,769 (262)
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Age and sea surface temperature from sediment core XP98-PC-2
, 2004 Age and sea surface temperature from sediment core XP98-PC-
Seki, Osamu +9 more
core +1 more source
ESA’s Climate Change Initiative (CCI) has released the third major version of the SST CCI Climate Data Record (CDR) which now spans over 40 years, using data from Advanced Very High Resolution Radiometer (AVHRR), Along Track Scanning Radiometer (ATSR), Sea and Land Surface Temperature Radiometer (SLSTR) instruments, Advanced Microwave Scanning ...
Embury, Owen +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Sea surface temperature reconstruction from sediment core GeoB1523-1
, 1999 Sea surface temperature reconstruction from sediment core GeoB2204-
Pflaumann, Uwe +3 more
core +1 more source
Solar cycle signals in sea level pressure and sea surface temperature [PDF]
Atmospheric Chemistry and Physics, 2010 We identify solar cycle signals in 155 years of global sea level pressure (SLP) and sea surface temperature (SST) data using a multiple linear regression approach.
I. Roy, J. D. Haigh
doaj
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Sea surface temperature differences (UK'37-TEX86) for sediment core 346-U1425, Japan Sea
, 2017 Sea surface temperature differences (UK'37-TEX86) for sediment core 346-U1425, Japan ...
Wittkopp, Frederike +11 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source