Results 141 to 150 of about 802,355 (333)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Investigation of models for large-scale meteorological prediction experiments [PDF]

open access: yes
Studies are reported of the long term responses of the model atmosphere to anomalies in snow cover and sea surface temperature. An abstract of a previously issued report on the computed response to surface anomalies in a global atmospheric model is ...
Spar, J.
core   +1 more source

Remote sensing of air-sea interactions [PDF]

open access: yes, 1984
A number of preliminary concepts for the measurement or inference of fluxes across the air-sea interface through remote sensing are proposed. All the methods are achievable from aircraft with state-of-the-art technology.
Atlas, D., Mollo-Christensen, E.
core   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Reconstruction of sea surface temperatures from the oxygen isotope composition of fossil planktic foraminifera. [PDF]

open access: yes, 2002
Knowledge of the historic surface temperature of sea water is of importance for the calibration of climate models. The oxygen isotope composition of the shells of several species of planktic foraminifera can be used as a measure for this sea surface ...
Davydova, N.   +7 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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