Results 131 to 140 of about 202,076 (312)
Variability of water masses and circulation in the subtropical North Atlantic [PDF]
, 1999 Observations of interannual variability in 18 Water (Talley and Raymer 1982) and Gulf Stream transport (Worthington 1977) motivate an ocean model sensitivity study. The North Atlantic circulation is simulated with a three-dimensional isopycnic coordinate
Marsh, R.
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Sea-level variability in the Caribbean Sea over the last century
, 2013 Mean sea level rise exposes coasts to increasing risks. For the Caribbean Sea, the regional and local sea-level behaviour is not well known. This study has investigated the sea level behavior in the region at different frequencies during the last century,
Torres Parra, R. Ricardo
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
, 2014 Bathymetric biodiversity patterns of marine benthic invertebrates and demersal fishes have been identified in the extant fauna of the deep continental margins.
Brown, Alastair, Thatje, Sven
core +1 more source
AnimalsThis study aimed to evaluate the effects of water temperature and catch frequency on biodiversity and distribution in the waters around Korea. We analyzed spatiotemporal catch data reported by fishermen and evaluated the fluctuations in the dominantly ...
Hyithaek Ceong, Inyeong Kwon
doaj +1 more source
Sea surface temperatures in waters surrounding Sweden
, 1974 One of the sub-projects within the sea ice research programme carried out at SMHI deals with the thermodynamics of the sea and the ice. In these studies the sea surface temperature plays a fundamental r ole. During the latest years considerable efforts have been made in order to obtain more temperature observations, in particular from the open sea ...
Thompson, Thomas +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source