Results 121 to 130 of about 202,076 (312)

Seasonal variability of the warm Atlantic Water layer in the vicinity of the Greenland shelf break [PDF]

open access: yes, 2014
The warmest water reaching the east and west coast of Greenland is found between 200?m and 600?m. Whilst important for melting Greenland's outlet glaciers, limited winter observations of this layer prohibit determination of its seasonality.
Kit M. Kovacs   +32 more
core   +1 more source

Research on Relationship Between Runoff of Upper Reaches of the Yellow River and Sea Surface Temperature and Atmospheric Circulation Characteristics

open access: yesRenmin Zhujiang, 2021
Precipitation in any watershed is a part of the global atmosphere and water cycle.Most of the water in the atmosphere comes from seawater evaporation.The amount of water vapor is directly related to the sea surface temperature (SST),which is the main ...
WANG Dan, PAN Hongzhong, BAI Yu
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Variability and uncertainty in measuring sea surface temperature

open access: yes, 2012
Sea Surface Temperature (SST) measurement is one of the most easily obtainable climate variables. However, it is challenging to meet the required absolute accuracy and long term stability whether the data are derived by in situ or satellite measurements.
Wimmer, Werenfrid
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Water characteristics in puddles and open waters in the fast ice area and its influence to marine environment

open access: yesAntarctic Record, 2007
Summer environments in puddles and open waters formed in the fast ice area near Syowa Station, Antarctica were observed. Small open waters formed in the fast ice were filled with low saline water. Low saline water was supplied by melting sea ice and snow.
Akihisa S. Otsuki
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

RRS "Discovery" Cruise D279, 04 Apr - 10 May 2004. A Transatlantic hydrography section at 24.5N [PDF]

open access: yes, 2005
The cruise report describes the acquisition and processing of transatlantic hydrographic, velocity, chemistry and other measurements made during three cruises in Spring 2004 at 24.5°N.
Cunningham, S.A.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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