Results 31 to 40 of about 32,884 (310)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Alan Branch, Elements of Port Operation and Management [PDF]

, 2015
Book ...
İNCAZ, Serap
core   +2 more sources

Chemical fire and explosion hazards at seaports: a review of human – causes, consequences and prevention strategies

Вестник Университета гражданской защиты МЧС Беларуси
Purpose. Seaports serve as critical centers for global trade and transportation; however, they are also prone to significant risks of chemical fire and explosion accidents.
Ван Нам Нго, Хуу Хиеу Нгуен, Ань Фан   +2 more
doaj   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Um Atlântico de Açúcares. Os portos do Norte de Portugal e o Novo Mundo

Nuevo mundo - Mundos Nuevos, 2016
This article studies the organization of an Atlantic port and the way in which the Northwestern Portuguese seaports were at the origin of innovative commercial activities that contributed to the construction of the Atlantic economy in the Early Modern ...
Amândio Jorge Morais Barros
doaj   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Benchmarking fish biodiversity of seaports with eDNA and nearby marine reserves

Conservation Letters
Coastal areas offer a diversity of habitats providing refugia and nursery for fish, promoting their biodiversity and associated contributions to people. Yet, natural coastlines are replaced by artificial infrastructures such as seaports and the influence
Stéphanie Manel, Laetitia Mathon, David Mouillot, Morgane Bruno, Alice Valentini, Gilles Lecaillon, Anais Gudefin, Julie Deter, Pierre Boissery, Alicia Dalongeville   +9 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

System Dynamics Approach to Global Shipping Emissions [PDF]

TransNav
This paper presents an improved System Dynamics (SD) model to assess the greenhouse gas (GHG) emission reduction measures between 2023 and 2050 at the container terminal of the Port of Koper.
Marin Hero, Peter Vidmar, Marko Perkovič   +2 more
doaj   +1 more source