Results 51 to 60 of about 32,884 (310)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Labour Market Developments in the Maritime Industry of the South Baltic Region [PDF]
, 2014 There are two aims of this study. The first is to outline the developments in the maritime economy and employment in the South Baltic Region, and the second to identify the emerging activities in the maritime industry and to reveal the prospects and ...
Bernacki, Dariusz
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Semantic Intelligence in a Seaport Context [PDF]
2018 IEEE/ACS 15th International Conference on Computer Systems and Applications (AICCSA), 2018 This research work proposes the framework for seaport partners to interact on a semantic level and scope related with jurisdictions/ecosystems and regions to share knowledge among partners. New steps towards dealing with the traditional common sense for managing or governing the seaport are required for assisting the new generation of managers and port
Ana Ximena Halabi Echeverry +2 more
openaire +2 more sources
Place branding of seaports in the Middle East [PDF]
, 2017 This paper analyses seaports’ brand personalities as a means of understanding similarities and differences of these important locations and their relationship with their host place image.
A Graham +70 more
core +2 more sources
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Strategic correlations for maritime clusters [PDF]
, 2019 Maritime clusters formulate appealing objects of study, for many viewpoints. At the same time, the theory is not homogenous nor compartmentalized, although some main themes do seem to be prevalent. The latter include innovation, competitiveness, strategy,
Koliousis, Ioannis +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source