Results 61 to 70 of about 2,844 (263)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Contemporary Economy, 2017 The duration of border control procedures related to the handling of freight transported by means of sea-road transport chains has become a significant component in competitiveness of seaports.
Michał Pluciński
doaj
Stages of government control development of seaports work in the Far East
Вестник Тамбовского университета. Серия: Гуманитарные науки, 2019 We used not only archival collections (Russian State Historical Archive of the Far East) as materials for the study, but also the works of the authors, which historically and consistently traced the development of domestic navigation, as well as the ...
V. A. Kurbenkov
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The Use of Social Media as a Marketing Communication Channel by the Largest Ports of the Baltic Sea Region [PDF]
TransNavSocial media is used by more and more organizations, including seaports, because digital communication channels are an important tool in creating the brand image and one of the ways to build good relationships with stakeholders.
Anna Kaminska, Przemyslaw Dmowski
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Handel morski i porty Brandenburgii-Prus w drugiej połowie XVII i w XVIII wieku.
Studia Maritima, 2015 In the years 1648–1653 the Brandenburg Hohenzollerns achieved the long-desired goal of their foreign policy: they got a direct access to the sea, but commercial benefits were rather scarce without the Oder estuary and Szczecin (Stettin). So they fought
Zygmunt Szultka
doaj +1 more source