Results 31 to 40 of about 71,650 (258)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Medical emergencies at sea: an analysis of ambulance-supported and autonomously performed operations by lifeboat crews

BMC Emergency Medicine, 2023
Background Very little data is available about the involvement of lifeboat crews in medical emergencies at sea. The aim of this study is to analyze the medical operations at sea performed by the Royal Netherlands Sea Rescue Institution (KNRM).
Daphne M. Messelink, Gert-Jan van der Ploeg, Theo van der Linden, Roos D. Flameling, Joost J. L. M. Bierens   +4 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Improving operational use of post-disaster damage assessment for Urban Search and Rescue by integrated graph-based multimodal remote sensing data analysis

Progress in Disaster Science
This work investigates the application of remote sensing technologies within the specific operational context of emergency urban search and rescue (USAR) efforts post-disaster. We thoroughly investigate two innovative methodologies, each tailored to meet
Sivasakthy Selvakumaran, Iain Rolland, Luke Cullen, Rob Davis, Joshua Macabuag, Charbel Abou Chakra, Nanor Karageozian, Amir Gilani, Christian Geiβ, Miguel Bravo-Haro, Andrea Marinoni   +10 more
doaj   +1 more source

An Information-Motivated Exploration Agent to Locate Stationary Persons with Wireless Transmitters in Unknown Environments

Sensors, 2021
Unmanned Aerial Vehicles (UAVs) show promise in a variety of applications and recently were explored in the area of Search and Rescue (SAR) for finding victims.
Daniel Barry, Andreas Willig, Graeme Woodward   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Safe Search and Rescue Operations Based on Autonomous Robots: A Systematic Review of the General System Architecture

IEEE Access
Over the past few years, remarkable progress has been made in Autonomous Robotic Systems (ARSs) due to their multidisciplinary nature and applications. Among the most in-demand applications is the Search and Rescue (SAR) task, particularly in high-risk ...
Abbas Aqeel Kareem, Ahmed Jabbar Abid, Dalal Abdulmohsin Hammood, Ali Abdulelah Al-Naji, Javaan Chahl   +4 more
doaj   +1 more source

A Location-Aware Waypoint-Based Routing Protocol for Airborne DTNs in Search and Rescue Scenarios

Sensors, 2018
In this paper, we propose GeoSaW, a delay-tolerant routing protocol for Airborne Networks in Search and Rescue scenarios. The protocol exploits the geographical information of UAVs to make appropriate message forwarding decisions.
Armir Bujari, Carlos T. Calafate, Juan-Carlos Cano, Pietro Manzoni, Claudio E. Palazzi, Daniele Ronzani   +5 more
doaj   +1 more source