Distant objects detected visually with optical filters [PDF]
Fluorescent coating aids visual daylight detection and identification of distant objects. An object appears as a blinking light when the area is alternately scanned with transmitting and obscuring filters.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Leeway of Shipping Containers at Different Immersion Levels [PDF]
The leeway of 20-foot containers in typical distress conditions is established through field experiments in a Norwegian fjord and in open-ocean conditions off the coast of France with wind speed ranging from calm to 14 m/s.
AD Kirwan +17 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
This work investigates the application of remote sensing technologies within the specific operational context of emergency urban search and rescue (USAR) efforts post-disaster. We thoroughly investigate two innovative methodologies, each tailored to meet
Sivasakthy Selvakumaran +10 more
doaj +1 more source
Background Very little data is available about the involvement of lifeboat crews in medical emergencies at sea. The aim of this study is to analyze the medical operations at sea performed by the Royal Netherlands Sea Rescue Institution (KNRM).
Daphne M. Messelink +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Assessment of Physical Activity in Search and Rescue Operations Using Accelerometer Based Technologies. [PDF]
Helicopter search and rescue crews (SARC) operate on a 24 hour shift with crew members either sleeping on-base or at home depending on their proximity to the base.
May, Gregory, Warrington, Giles
core
Current state of the art of unmanned systems with potential to be used for radiation measurements and sampling: ERNCIP thematic group Radiological and nuclear threats to critical infrastructure - Task 3 deliverable 1 [PDF]
There is a significant potential in the use of unmanned remote controlled vehicles in sampling and measuring radiological events. No attempts to standardise sampling and measurement methods using these types of vehicles have been made so far.
GARDESTIG M. +3 more
core +1 more source

