Results 51 to 60 of about 71,650 (258)

Rescue Robots for Casualty Extraction: A Comprehensive Review

open access: yesIEEE Access
The development of robotic systems for search and rescue (SAR) operations holds great potential in reducing risks to rescue workers and enhancing the likelihood of successful rescue operations.
Roni Permana Saputra   +6 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

An Autonomous Drone for Avalanche Search and Rescue: Integrating ArduPilot and Tracking-Beacon Detection

open access: yesIEEE Access
Avalanches claim numerous lives annually, underscoring the critical need for rapid and reliable rescue solutions. This paper presents an innovative autonomous drone system explicitly designed to enhance avalanche search and rescue (SAR) operations in ...
Jedrzej Stasik, Tomasz Szandala
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The modified crABCDE treatment algorithm as recommendation in extreme cold

open access: yesResuscitation Plus
Trauma care prioritizes life-threatening conditions using the ABCDE algorithm based on the principle “treat first what kills first”. As for catastrophic hemorrhage, a leading preventable cause of death in trauma, modifications of this algorithm are ...
Raimund Lechner   +5 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Search-and-Rescue Rendezvous

open access: yes, 2016
We consider a new type of asymmetric rendezvous search problem in which Agent II needs to give Agent I a `gift' which can be in the form of information or material. The gift can either be transfered upon meeting, as in traditional rendezvous, or it can be dropped o? by II at a location he passes, in the hope it will be found by I.
Leone, Pierre, Alpern, Steve
openaire   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

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