Results 51 to 60 of about 2,873,297 (289)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Applied SciencesDemagnetization faults in direct-drive permanent magnet synchronous motors (DDPMSM) can cause significant performance degradation and unplanned downtime.
Caixia Gao +3 more
doaj +1 more source
China Seismo-Electromagnetic Satellite search coil magnetometer data and initial results
Earth and Planetary Physics, 2018 Four levels of the data from the search coil magnetometer (SCM) onboard the China Seismo-Electromagnetic Satellite (CSES) are defined and described. The data in different levels all contain three components of the waveform and/or spectrum of the induced ...
Qiao Wang +6 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
[Design and Investigation of a Hybrid Optical Resonator for Medium Energy COIL] [PDF]
, 2007 High brightness laser radiation of chemical oxygen iodine lasers (COIL) requires resonator types especially adapted to low gain medium and rectangular cavity geometry.
Grünewald, Karin +3 more
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
BMC Psychiatry, 2019 Background The current study aims to systematically assess and compare the antidepressant outcomes of repetitive transcranial magnetic stimulation (rTMS) with the figure-of-eight (F8)-coil and deep transcranial magnetic stimulation (DTMS) with the H1 ...
Helena M. Gellersen +1 more
doaj +1 more source
Experimental Assessment of a Magnetic Induction-Based Receiver for Magnetic Communication
IEEE Access, 2022 This paper presents the topology of a novel approach to magnetic communication using a differential magnetic induction (MI)-based receiver and a differential MI receiving sensor. In this paper, a differential MI sensor based on two ferromagnetic cores is
Jang-Yeol Kim +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source