Results 51 to 60 of about 182,643 (329)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Search Engine Optimization Techniques
International Journal For Multidisciplinary Research, 2023 The search engine plays a vital role in E-marketing in a modern-day scenario. The search engine provides us the search results. It shows the results as a list. The ultimate goal of a search engine is to optimize the search result. The search engine optimizes the search results based on relevancy.
Rahul Dhiman -, Naveen Bansal -
openaire +1 more source
Multiplicative Bidding in Online Advertising [PDF]
, 2014 In this paper, we initiate the study of the multiplicative bidding language adopted by major Internet search companies. In multiplicative bidding, the effective bid on a particular search auction is the product of a base bid and bid adjustments that are ...
Bateni, MohammadHossein +3 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
ARA: Revista de Investigación en Turismo, 2021 The websites of destination marketing organizations are very frequently the first contact between the tourist and the destination.
Lucia Molina Pérez +2 more
doaj
Sukkur IBA Journal of Computing and Mathematical Sciences, 2022 Search Engines (SEs) have become the most significant tool for retrieving information from the World Wide Web (WWW) against user-generated queries. Presently, the data available on the Internet is growing exponentially in three different dimensions i.e.
Muhammad Iqbal +4 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
SEO strategies in booksellers sector
Intangible Capital, 2009 The Internet has consolidated as a new commercial and marketing channel due to the advance of Information and Communication Technologies and the saturation of conventional media channels.
Ferran Sabate +3 more
doaj +1 more source
, 2009 We explore the use of the Cell Broadband Engine (Cell/BE for short) for combinatorial optimization applications: we present a parallel version of a constraint-based local search algorithm that has been implemented on a multiprocessor BladeCenter machine ...
Abreu, Salvator +2 more
core +4 more sources