Results 61 to 70 of about 85,436,355 (282)
Memorial March Discussion, 1969
, 1969 Members Memphis Search for Meaning Committee and their younger children discuss their observations about the events surrounding various marches in ...
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 2014 Objective : The purpose of this study was to explore the associations between meaning making and psychological adjustment in 127 women who experienced a miscarriage. Design : A longitudinal and controlled study design was employed. Main outcome measures :
Nikcevic, Ana V. +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Do Sources of Meaning Differentially Predict Search for Meaning, Presence of Meaning, and Wellbeing [PDF]
, 2015 Meaning in life is vital for human wellbeing. Research has examined important sources of meaning: however, it has not yet investigated whether certain sources of meaning might be more predictive of overall meaning and wellbeing. A community sample of 247
Grouden, Melissa E., Jose, Paul E.
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BMC Public HealthObjective Loneliness is a growing mental health challenge among youth specially who are residing in urban areas. Factors that might help them combat loneliness need to be investigated.
Raina Chhajer +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Analysis of the Elements of Logotherapy in Attar Neyshaburi's Mantiq al-Tayr [PDF]
ادبیات عرفانیThe Mantiq al-Tayr, as a seminal work of mystical literature, symbolizes humanity’s quest for meaning and truth. To To explore the multifaceted nature of this text, this study examines the relationship between the theory of logotherapy and Mantiq al-Tayr.
Farideh Davoudimoghadam
doaj +1 more source