Results 171 to 180 of about 7,618,915 (290)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

The Impact of Mental Fatigue on Decision-Making Abilities, Visual Search Strategies, and Simple Reaction Time in Handball Players: A Randomized Crossover Study. [PDF]

Sports (Basel)
Kim J, Yook D, Han S.
europepmc   +1 more source

MeSH and text-word search strategies: precision, recall, and their implications for library instruction. [PDF]

J Med Libr Assoc, 2022
DeMars MM, Perruso C.
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Adaptive resetting for informed search strategies and the design of non-equilibrium steady-states. [PDF]

Nat Commun
Keidar TD, Blumer O, Hirshberg B, Reuveni S.   +3 more
europepmc   +1 more source

Investigation of text-mining methodologies to aid the construction of search strategies in systematic reviews of diagnostic test accuracy-a case study. [PDF]

Res Synth Methods, 2023
O'Keefe H, Rankin J, Wallace SA, Beyer F.   +3 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Search strategies for systematic reviews in reproductive medicine: a narrative review and practical guide. [PDF]

J Assist Reprod Genet
Vireque A, Stolakis V, Berteli T, Bertero M, Kofinas J.   +4 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evolutionary salp swarm algorithm with multi-search strategies and advanced memory mechanism for solving global optimization and complex engineering problems. [PDF]

Sci Rep
Zamani H.
europepmc   +1 more source