Results 51 to 60 of about 377,532 (310)
An Interdisciplinary Inquiry into the Foundations of Trademark Law [PDF]
The assessment of any legal system, such as trademark law, requires a comprehensive understanding of that system, and this can be made possible only through awareness of the objectives and foundations of that system. This awareness in trademark law helps
Sh. Kasnavi
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Weed Search and Control: Theory and Application [PDF]
The detectability of invasive organisms influences the costs and benefits of alternative control strategies, and the feasibility of eradicating an infestation.
Spring, Daniel +3 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Sociology of Alcohol Consumption – In Search of a Theory
Alcohol consumption takes place in society and because of society. The “social” aspect of this phenomenon gives a meaning that manifests itself in the framework of interaction.
Erik Brezovec
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
In search of a nativist theory of second language acquisition
This article illustrates the search for a theory of second language acquisition. It is the task of the applied linguist to investigate any discipline which can shed light on this problem.
Van der Wait, Johann L.
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
In the modern era of informatics, where data are very important, efficient management of data is necessary and critical. Two of the most important data management techniques are searching and data ordering (technically sorting).
Anurag Dutta +3 more
doaj +1 more source

