Results 71 to 80 of about 17,504,389 (343)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
An Improved Potential Game Theory Based Method for Multi-UAV Cooperative Search
IEEE Access, 2020 Unmanned Aerial Vehicle (UAV) has been widely used in a variety of application, and the target search is one of the hot issues in the UAV research fields.
Jianjun Ni +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Systematic Literature Review: Theory Perspective in Lean Manufacturing Performance
Management Systems in Production Engineering, 2023 This review examines the trend of applying theories in LM performance and offers the latest recapitulation of related theories in LM performance. The methodology is based on Preferred Reporting Items for Systematic Reviews (PRISMA) to search for multiple
Aripin Norhana Mohd +5 more
doaj +1 more source
New perspectives on Web search engine research [PDF]
, 2012 Purpose–The purpose of this chapter is to give an overview of the context of Web search and search engine-related research, as well as to introduce the reader to the sections and chapters of the book.
Lewandowski, Dirk
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Adapting Search Theory to Networks [PDF]
, 2001 The CSE is interested in the general problem of locating objects in networks. Because of their exposure to search theory, the problem they brought to the workshop was phrased in terms of adapting search theory to networks.
Alspach, Brian
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
On search theory and customers
Económica, 2000 This paper studies a simple model of decentralized exchange where consumers have to search for a seller that provides the services they want. Once a buyer finds one of these "good" stores, a customer relationship between the two develops.
Huberto María Ennis
doaj
Frege's Theory of Relations and the Search for a Workable Alternative
Crítica, 2018 El artículo brinda una reconstrucción de la ontología fregeana y, tras someterla a una crítica, hace someras indicaciones para una alternativa a la misma. El problema aquí tratado aparece ya planteado por el propio Frege en “Uber Begriff und Gegenstand”,
Lorenzo Peña
doaj +1 more source