Results 81 to 90 of about 377,532 (310)
Ordered search in differentiated markets [PDF]
This note presents an ordered search model in which consumers search both for price and product fitness. We construct an equilibrium in which there is price dispersion and prices rise in the order of search.
Zhou, J., Zhou, Jidong
core
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Search Funds and Agency Theory: an empirical analysis [PDF]
openIn the contemporary landscape of asset classes available, the search fund model represents an attractive investment vehicle and opportunity suited both for investors looking for high returns and for young and talented entrepreneurs willing to become ...
MOCCIA, ANDREA
core
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
In Search of a Theory of Polarization: Lessons from Venezuela, 1999-2005
nnb
Javier Corrales
doaj +1 more source
Search Pathways to Innovation [PDF]
Organizational search processes is an important source of firm level heterogeneity in evolutionary - behavioural theory. Combining insights from established and recent evolutionary-behavioural theory we propose that R&D and managerial perceptions ...
Tommy Clausen
core
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Sequential Search with Incompletely Informed Consumers: Theory and Evidence from Retail Gasoline Markets [PDF]
A large variety of markets, such as retail markets for gasoline or mortgage markets, are characterized by a small number of firms offering a fairly homogenous product at virtually the same cost, while consumers, being uninformed about this cost ...
Maarten Janssen +2 more
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Nonstandard Foundations of Equilibrium Search Models [PDF]
We develop an equilibrium sequential search model which includes most of the literature as special cases. In particular, the model can accommodate heterogeneity in buyers’ search costs and demand functions and firms’ cost functions, with general demand ...
Michael T. Rauh
core

