Results 51 to 60 of about 2,633,104 (290)

Data handling methods and target detection results for multibeam and sidescan data collected as part of the search for SwissAir Flight 111 [PDF]

open access: yes, 1999
The crash of SwissAir Flight 111, off Nova Scotia in September 1998, triggered one of the largest seabed search surveys in Canadian history. The primary search tools used were sidescan sonars (both conventional and focussed types) and multibeam sonars ...
Bradford, Jim   +5 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Stretching EU competition law tools for search engines and social networks

open access: yesInternet Policy Review, 2015
Because of their multi-sided and dynamic nature, the application of competition law to online platforms may prove challenging. The paper maintains that existing competition concepts are flexible enough to be adequately applied to search engines and ...
Inge Graef
doaj   +1 more source

Ontology ranking based on the analysis of concept structures [PDF]

open access: yes, 2005
In view of the need to provide tools to facilitate the reuse of existing knowledge structures such as ontologies, we present in this paper a system, AKTiveRank, for the ranking of ontologies.
Alani, Harith, Brewster, Christopher
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

METHODOLODICAL TOOLS FOR ORGANIZING THE PROCESS OF STAFF1 SEARCH AND SELECTION

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2015
The relevance and the basic stages to meet the demand in personnel in the contemporary economy were determined. The necessity and requirements for the formation of maps of competencies as tools for personnel selection were proved and generalized.
T. Bilorus
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Using genetic algorithms to generate test sequences for complex timed systems [PDF]

open access: yes, 2012
The generation of test data for state based specifications is a computationally expensive process. This problem is magnified if we consider that time con- straints have to be taken into account to govern the transitions of the studied system.
A Loureiro   +32 more
core   +1 more source

GASSST: global alignment short sequence search tool [PDF]

open access: yesBioinformatics, 2010
Abstract Motivation: The rapid development of next-generation sequencing technologies able to produce huge amounts of sequence data is leading to a wide range of new applications. This triggers the need for fast and accurate alignment software.
Rizk, Guillaume, Lavenier, Dominique
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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