Results 51 to 60 of about 558,831 (256)

BLASTO: a tool for searching orthologous groups [PDF]

open access: yesNucleic Acids Research, 2007
We present BLAST on Orthologous groups (BLASTO), a modified BLAST tool for searching orthologous group data. It treats each orthologous group as a unit and outputs a ranked list of orthologous groups instead of single sequences. By filtering out redundancy and putative paralogs, sequence comparisons to orthologous groups, instead of to single sequences
Yi Zhou, Laura F. Landweber
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Digital Tools in Education: From Data Search to Publications

open access: yesБиблиосфера
The article deals with the urgent problem of integrating university libraries into the research process via the development of the academic community’s digital competence.
M. B. Mishanina
doaj   +1 more source

Stretching EU competition law tools for search engines and social networks

open access: yesInternet Policy Review, 2015
Because of their multi-sided and dynamic nature, the application of competition law to online platforms may prove challenging. The paper maintains that existing competition concepts are flexible enough to be adequately applied to search engines and ...
Inge Graef
doaj   +1 more source

New Search Tools

open access: yes, 2021
Slides from a presentation to the Connecticut Library Consortium (CLC) Academic Roundtable, Feb 18, 2021.
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

METHODOLODICAL TOOLS FOR ORGANIZING THE PROCESS OF STAFF1 SEARCH AND SELECTION

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2015
The relevance and the basic stages to meet the demand in personnel in the contemporary economy were determined. The necessity and requirements for the formation of maps of competencies as tools for personnel selection were proved and generalized.
T. Bilorus
doaj   +1 more source

Panopticon as an eLearning support search tool [PDF]

open access: yesProceedings of the SIGCHI Conference on Human Factors in Computing Systems, 2014
We present an evaluation of Panopticon, a video surrogate system, as an online eLearning support search tool for finding information within video lectures. A comparison was made with a standard video player (YouTube) in two scenarios with two classes of users: revision students and independent learners.
James Nicholson   +3 more
openaire   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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