Results 81 to 90 of about 2,633,104 (290)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Rational Deployment of CSP Heuristics [PDF]
, 2011 Heuristics are crucial tools in decreasing search effort in varied fields of AI. In order to be effective, a heuristic must be efficient to compute, as well as provide useful information to the search algorithm.
Shimony, Solomon Eyal, Tolpin, David
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
PMS: A Panoptic Motif Search Tool
PLoS ONE, 2013 Identification of DNA/Protein motifs is a crucial problem for biologists. Computational techniques could be of great help in this identification. In this direction, many computational models for motifs have been proposed in the literature.One such important model is the (l,d) motif model.
Hieu Dinh, Sanguthevar Rajasekaran
openaire +4 more sources
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
A strategy for evaluating search of “Real” personal information archives [PDF]
, 2011 Personal information archives (PIAs) can include materials from many sources, e.g. desktop and laptop computers, mobile phones, etc. Evaluation of personal search over these collections is problematic for reasons relating to the personal and private ...
Chen, Yi, Jones, Gareth J.F.
core
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
KI- und zitationsbasierte Tools für die Literatursuche
GMS Medizin – Bibliothek – InformationVarious newer tools use AI and/or citation-based algorithms to display a small number of “good” hits. You can either start with a specific paper (Connected Papers, ResearchRabbit) or you can enter a question (SciSpace, Elicit).
Braun, Volker
doaj +1 more source
Connecting to Internet–Search Tools [PDF]
International Nursing Review, 1998 The amount of information on the Internet is growing by the nanosecond. It is no longer expeditious to “surf” site to site now that automated convenient‐to‐use search tools can find the information you are looking for swiftly. Unfortunately, no one tool covers the entire worldwide web (www), much less the entire Internet.
openaire +3 more sources
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source