Results 41 to 50 of about 178,130 (288)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A novel approach for the prediction of treadmill test in cardiology using data mining algorithms implemented as a mobile application

open access: yesIndian Heart Journal, 2018
Objective: To develop a mobile app called “TMT Predict” to predict the results of Treadmill Test (TMT), using data mining techniques applied to a clinical dataset using minimal clinical attributes. To prospectively test the results of the app in realtime
A. Jerline Amutha   +2 more
doaj   +1 more source

Improving Accessibility of Archived Raster Dictionaries of Complex Script Languages

open access: yes, 2014
We propose an approach to index raster images of dictionary pages which in turn would require very little manual effort to enable direct access to the appropriate pages of the dictionary for lookup.
Alam, Sawood   +2 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Architecture modeling for system collaborative combat based on unified architecture framework (UAF) [PDF]

open access: yesZhihui kongzhi yu fangzhen
Facing the continuous improvement of war complexity under the trend of system-of-systems confrontation,this paper introduces MBSE to the modeling design of complex system-of-systems combat. Adopting Unified Architecture Framework, a modeling method based
LI Delin, ZHANG Yuchen, WANG Jun, LIU Naihao
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

ONTOLOGY OF COMPUTATIONAL EXPERIMENT ORGANIZATION IN PROBLEMS OF SEARCHING AND SORTING

open access: yesÌнформаційні технології в освіті, 2011
Ontologies are a key technology of semantic processing of knowledge. We examine a methodology of ontology’s usage for the organization of computational experiment in problems of searching and sorting in studies of the course "Basics of algorithms and ...
A. Spivakovsky, N. Osipova
doaj  

Data sorting [PDF]

open access: yes, 2005
Ovaj rad prikazuje jedno od rješenja problema sortiranja podataka u jednodimenzionalnom polju (nizu) elemenata. U praksi se često pojavljuje potreba za sortiranjem podataka te se zbog toga traži što efikasniji i brži algoritam.
A. Baumgartner, S. Poljak
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Minimum and maximum against k lies

open access: yes, 2010
A neat 1972 result of Pohl asserts that [3n/2]-2 comparisons are sufficient, and also necessary in the worst case, for finding both the minimum and the maximum of an n-element totally ordered set.
A. Pelc   +6 more
core   +1 more source

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