Results 61 to 70 of about 25,195 (291)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Improved sorting networks with O(log n) depth [PDF]

The sorting network described by Ajtai, KomlOs and Szemeredi was the first to achieve a depth of O(Iog n). The networks introduced here are simplifications and improvements based strongly on their work.
Paterson, Michael S.
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Textual and chemical information processing: different domains but similar algorithms

Information Research: An International Electronic Journal, 2000
This paper discusses the extent to which algorithms developed for the processing of textual databases are also applicable to the processing of chemical structure databases, and vice versa.
Peter Willett
doaj  

Sorting and Searching

, 1973
Chapter 5 is concerned with sorting into order, internal sorting and external sorting. Chapter 6 deals with the problem of searching for specified items in tables or files. It is subdivided into methods which search sequentially, or by comparison of keys,
D. Knuth
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

iFLEX: A Fully Open-Source, High-Density Field-Programmable Gate Array (FPGA)-Based Hardware Co-Processor for Vector Similarity Searching

IEEE Access, 2019
Vector similarity searching consists of comparing a query vector against a high volume of entries in a reference data set, according to a chosen similarity metric such as the L1-norm, L2-norm, or Hamming distance.
Ludovico Minati, Vardan Movsisyan, Matthew Mccormick, Khachatur Gyozalyan, Tigran Papazyan, Hrach Makaryan, Stefano Aldrigo, Taron Harutyunyan, Hayk Ghaltaghchyan, Chris Mccormick, Mick Fandrich   +10 more
doaj   +1 more source

Combined Heat and Power Economic Emission Dispatch Using Hybrid NSGA II-MOPSO Algorithm Incorporating an Effective Constraint Handling Mechanism

IEEE Access, 2020
This research work proposes a synergistic hybrid metaheuristic algorithm a merger of Nondominated Sorting Genetic Algorithm II and Multiobjective Particle Swarm Optimization algorithm for solving the highly complicated combined heat and power economic ...
Arunachalam Sundaram
doaj   +1 more source

Sorting and searching in the presence of memory faults (without redundancy)

, 2004
We investigate the design of algorithms resilient to memory faults, i.e., algorithms that, despite the corruption of some memory values during their execution, are able to produce a correct output on the set of uncorrupted values.
ITALIANO G, FINOCCHI, Irene, Giuseppe F. Italiano, Irene Finocchi, FINOCCHI I   +4 more
core   +1 more source