Results 81 to 90 of about 185,887 (355)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Textual and chemical information processing: different domains but similar algorithms

open access: yesInformation Research: An International Electronic Journal, 2000
This paper discusses the extent to which algorithms developed for the processing of textual databases are also applicable to the processing of chemical structure databases, and vice versa.
Peter Willett
doaj  

iFLEX: A Fully Open-Source, High-Density Field-Programmable Gate Array (FPGA)-Based Hardware Co-Processor for Vector Similarity Searching

open access: yesIEEE Access, 2019
Vector similarity searching consists of comparing a query vector against a high volume of entries in a reference data set, according to a chosen similarity metric such as the L1-norm, L2-norm, or Hamming distance.
Ludovico Minati   +10 more
doaj   +1 more source

Combined Heat and Power Economic Emission Dispatch Using Hybrid NSGA II-MOPSO Algorithm Incorporating an Effective Constraint Handling Mechanism

open access: yesIEEE Access, 2020
This research work proposes a synergistic hybrid metaheuristic algorithm a merger of Nondominated Sorting Genetic Algorithm II and Multiobjective Particle Swarm Optimization algorithm for solving the highly complicated combined heat and power economic ...
Arunachalam Sundaram
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Unified Hardware-Software Complex Of Modern Learning Materials Creation And Collection Automatization

open access: yesÌнформаційні технології в освіті, 2009
The article analyzes modern learning materials (MLM) creation problems and the existing tools for such materials creation, their weaknesses and suggests ways to address them.
V. V. Polinovskyi, V. A. Gerasymenko
doaj  

MOEICA: Enhanced multi-objective optimization based on imperialist competitive algorithm [PDF]

open access: yesIranian Journal of Optimization, 2017
In this paper, a multi-objective enhanced imperialist competitive algorithm (MOEICA) is presented. The main structures of the original ICA are employed while some novel approaches are also developed.
AmirAli Nazari, ali deihimi
doaj  

Printed Arabic Words Recognition Using Genetic Algorithm

open access: yesالأستاذ, 2016
The automatic recognition of  text on scanned images has enabled many application such as searching for words in large volumes of  documents, automatic sorting of postal mail, and convenient editing of previously printed documents.
Assist.Teach.Rasha H.Ali
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Designing classes’ interfaces for neural network graph model

open access: yesТруды Института системного программирования РАН, 2019
An approach to testing artificial neural networks is described. The model of neural network is based on graph theory, and operations that are used in theoretical works devoted to graphs, trees, paths, cycles, and circuits.
Yuri Leonidovich Karpov   +4 more
doaj   +1 more source

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