Results 81 to 90 of about 185,887 (355)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Textual and chemical information processing: different domains but similar algorithms
This paper discusses the extent to which algorithms developed for the processing of textual databases are also applicable to the processing of chemical structure databases, and vice versa.
Peter Willett
doaj
Vector similarity searching consists of comparing a query vector against a high volume of entries in a reference data set, according to a chosen similarity metric such as the L1-norm, L2-norm, or Hamming distance.
Ludovico Minati +10 more
doaj +1 more source
This research work proposes a synergistic hybrid metaheuristic algorithm a merger of Nondominated Sorting Genetic Algorithm II and Multiobjective Particle Swarm Optimization algorithm for solving the highly complicated combined heat and power economic ...
Arunachalam Sundaram
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The article analyzes modern learning materials (MLM) creation problems and the existing tools for such materials creation, their weaknesses and suggests ways to address them.
V. V. Polinovskyi, V. A. Gerasymenko
doaj
MOEICA: Enhanced multi-objective optimization based on imperialist competitive algorithm [PDF]
In this paper, a multi-objective enhanced imperialist competitive algorithm (MOEICA) is presented. The main structures of the original ICA are employed while some novel approaches are also developed.
AmirAli Nazari, ali deihimi
doaj
Printed Arabic Words Recognition Using Genetic Algorithm
The automatic recognition of text on scanned images has enabled many application such as searching for words in large volumes of documents, automatic sorting of postal mail, and convenient editing of previously printed documents.
Assist.Teach.Rasha H.Ali
doaj +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Designing classes’ interfaces for neural network graph model
An approach to testing artificial neural networks is described. The model of neural network is based on graph theory, and operations that are used in theoretical works devoted to graphs, trees, paths, cycles, and circuits.
Yuri Leonidovich Karpov +4 more
doaj +1 more source

