Results 81 to 90 of about 177,412 (290)

Designing classes’ interfaces for neural network graph model

Труды Института системного программирования РАН, 2019
An approach to testing artificial neural networks is described. The model of neural network is based on graph theory, and operations that are used in theoretical works devoted to graphs, trees, paths, cycles, and circuits.
Yuri Leonidovich Karpov, Irina Anatolievna Volkova, Alexey Alexandrovich Vylitok, Leonid Evgenievich Karpov, Yuri Gennadievich Smetanin   +4 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Managing Contributions to the Unified Astronomy Thesaurus

EPJ Web of Conferences, 2018
The Unified Astronomy Thesaurus (UAT) project managers have long defined the UAT as "an open, interoperable, and community-supported thesaurus." How do we solicit the detailed, comprehensive, and consistent community feedback that is required to keep the
Frey Katie, Weissman Sarah, Kern Barbara, Lagerstrom Jill, Peek Josh, Accomazzi Alberto   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CD34-positive cells and their subpopulations characterized by flow cytometry analyses on the bone marrow of healthy allogenic donors

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Counting and separating hematopoietic stem cells from different sources has importance for research and clinical assays. Our aims here were to characterize and quantify hematopoietic cell populations in marrow donors and to ...
Jerusa Martins Carvalho, Marlon Knabben de Souza, Valéria Buccheri, Cláudia Viviane Rubens, José Kerbauy, José Salvador Rodrigues de Oliveira   +5 more
doaj   +1 more source

Using the Complete Sequences for Sorting Natural Numbers

Известия Иркутского государственного университета: Серия "Математика", 2017
Complete sequences are defined as infinite sequences of natural numbers, with the help of which it is possible to represent any other natural number.
Y. N. Artamonov
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Explanation of Avicenna’s Personality and Works from the Point of View of His Unknown Student, Abu Muḥammad ʿAbdullāh al-ʾAzdī [PDF]

Journal of Research on History of Medicine
Avicenna’s is well known in the world as one of the famous physicians and philosophers. After the publication of the book Al-Mā’a authored by Abu Muḥammad al-ʾAzdī (d. 456 AH), it became clear that Abu Muḥammad al-ʾAzdī was one of Avicenna’s students. In
Moallemi Moallemi, Morteza Darabinia, Hossein Jalahi   +2 more
doaj   +1 more source