Results 11 to 20 of about 27,805 (244)

The role of melatonin in mood disorders [PDF]

, 2015
Melatonin (N-acetyl-5-methoxytryptamine) has been discovered as a hormone secreted by the pineal gland, even though it is also synthetized in various other organs, tissues, and cells.
Cavuto, Marilde, De Berardis, Domenico, Di Giannantonio, Massimo, Di Nicola, Marco, Fornaro, Michele, Girinelli, Gabriella, Iasevoli, Felice, Martinotti, Giovanni, Mazza, Monica, Orsolini, Laura, Perna, Giampaolo, Piersanti, Monica, Serroni, Nicola, Tomasetti, Carmine, Valchera, Alessandro   +14 more
core   +1 more source

Cognitive and behavioral predictors of light therapy use [PDF]

, 2012
Objective: Although light therapy is effective in the treatment of seasonal affective disorder (SAD) and other mood disorders, only 53-79% of individuals with SAD meet remission criteria after light therapy.
A Bandura, A Baundra, A Tuunainen, AJ Claxton, Antonio Verdejo García, BH Marcus, BH Marcus, BT Mausbach, BW Lundahl, C Abraham, CJ Stepnowsky Jr, DD Burns, DD Burns, EE Michalak, EE Michalak, EL Worthington, G Pail, GT Wilson, I Yovel, JA Sirey, JE Maddux, JO Prochaska, JO Prochaska, JO Prochaska, JT Austin, Julie A. Schumacher, Kathryn A. Roecklein, KJ Rohan, L Radloff, M Conner, M Fishbein, M Terman, ME Thase, measurement Murray G. Seasonality: the importance of longitudinal, Megan A. Miller, MM Weissman, MR DiMatteo, MS Aloia, N Watanabe, Natalie C. Ernecoff, NC Gyurcsik, P Sheeran, P Sheeran, PJ Schwartz, R Flory, RA Neimeyer, RN Golden, RW Lam, TD Borkovec, WR Miller   +49 more
core   +4 more sources

Direct health care costs of treating seasonal affective disorder: a comparison of light therapy and fluoxetine. [PDF]

, 2012
Objective. To compare the direct mental health care costs between individuals with Seasonal Affective Disorder randomized to either fluoxetine or light therapy. Methods. Data from the CANSAD study was used.
Browne, Gina, Cheung, Amy, Dewa, Carolyn, Enns, Murray W, Lam, Raymond W, Levitan, Robert D, Levitt, Anthony, Michalak, Erin E, Morehouse, Rachel L   +8 more
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Seasonal Affective Disorder and Seasonality: A Review [PDF]

, 2012
Seasonal affective disorder is a condition where depressions in fall and winter alternate with nondepressed periods in the spring and summer. The Degree to which seasonal changes affect mood, energy, sleep, appetite, food preference, or the wish to ...
Sher, Leo, M.D.
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

A szezonális depresszió etiopatologiája és terápiás lehetóségei [PDF]

, 2016
To understand the etiology of seasonal affective disorder (SAD) heterogeneous biological, psychological and environmental mechanisms needs to be considered.
Bagdy, György, Gonda, Xénia, Molnár, Eszter, Rihmer, Zoltán   +3 more
core  

Early clinical predictors and correlates of long-term morbidity in bipolar disorder [PDF]

, 2017
OBJECTIVES: Identifying factors predictive of long-term morbidity should improve clinical planning limiting disability and mortality associated with bipolar disorder (BD).
Baldessarini, R. J., DE CHIARA, Lavinia, Girardi, Paolo, Koukopoulos, A. E., Koukopoulos, Alexia, Reginaldi, D., Sani, Gabriele, Serra, Giulia, Tondo, L.   +8 more
core   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

SAD Management in Lewiston, ME [PDF]

, 2017
Seasonal affective disorder may be a significant issue in Lewiston, ME due to it\u27s latitude. In addition, lack of transportation and poverty are also issues in this community. This project attempts to address treatment and increase awareness of SAD in
Deeb, Ashley L
core   +1 more source