Results 81 to 90 of about 27,929 (280)

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

Melatonin synthesis in the human pineal gland [PDF]

, 2007
Poster presentation: The mammalian pineal organ is a peripheral oscillator, depending on afferent information from the so-called master clock in the suprachiasmatic nuclei of the hypothalamus.
Ackermann, Katrin, Bux, Roman, Kauert, Gerold, Rüb, Udo, Stehle, Jörg H.   +4 more
core   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source

Occurrence of suicide and seasonal variation Ocorrência de suicídio e variação sazonal

Revista de Saúde Pública, 1998
OBJECTIVE: To review the estimated suicide rates for the Region Metropolitan, the main socio-political center in Chile, for the period 1979-1994, and to determine whether they follow a seasonal pattern.
Pedro Retamal C., Derek Humphreys
doaj   +1 more source

Mice with reduced DAT levels recreate seasonal-induced switching between states in bipolar disorder. [PDF]

, 2018
Developing novel therapeutics for bipolar disorder (BD) has been hampered by limited mechanistic knowledge how sufferers switch between mania and depression-how the same brain can switch between extreme states-described as the "holy grail" of BD research.
A Anand, A Must, Aniek Joosen, , B Barbini, B Wang, Benedetto Romoli, CA McClung, CE Begley, D Dulcis, D Dulcis, D Landgraf, D Sit, Davide Dulcis, Esther Schrurs, F Cassidy, FM Jacobsen, FM Volpe, G Leach, G Majumdar, G Molnar, G Parker, HC Lee, HJ Lee, HK Sayer, HP Blumberg, J Enkhuizen van, J Enkhuizen van, J Enkhuizen van, J Enkhuizen van, J Enkhuizen van, JA Sherman, Jared W. Young, JC Bensadoun, JC Wu, Jordy van Enkhuizen, JW Young, JW Young, JW Young, JW Young, K Roybal, LD Grandin, M Adida, MB Keller, N Takei, NE Rosenthal, P McGuffin, PA Geoffroy, RE Bender, Richard F. Sharp, RM Post, RT Mulder, RW Lam, S Flaisher-Grinberg, S Horschitz, S Malkoff-Schwartz, S Pellow, SA Barnes, SA Barnes, SE Knapen, T Kasahara, TA Greenwood, TA Greenwood, TD Aumann, TD Gould, TT Postolache, X Zhuang, ZA Cope, Zackary A. Cope   +67 more
core   +1 more source

Early evolutionary history of the seed

Biological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman, Alan R. T. Spencer, Jason Hilton   +2 more
wiley   +1 more source

Studying interspecific population synchrony: current status and future perspectives

Ecography, EarlyView.
Interspecific population synchrony, or co‐fluctuations in the population dynamics and demographic parameters of different species, is an important ecological phenomenon with major implications for the stability of communities and ecosystems. It is also central in the context of biodiversity loss, as interspecific synchrony can influence how ecological ...
Ragnhild Bjørkås, Ivar Herfindal, Marlène Gamelon, Aline Magdalena Lee   +3 more
wiley   +1 more source

Occurrence of suicide and seasonal variation

Revista de Saúde Pública, 1998
OBJECTIVE: To review the estimated suicide rates for the Region Metropolitan, the main socio-political center in Chile, for the period 1979-1994, and to determine whether they follow a seasonal pattern.
Retamal C. Pedro, Humphreys Derek
doaj  

Forecasting heart failure: Seasonal alignment of heart failure outcomes in New York

ESC Heart Failure, Volume 12, Issue 2, Page 819-831, April 2025.
Abstract Background Seasonal variations have been observed in heart failure (HF) hospitalization. Numerous explanatory mechanisms have been proposed, but no prior studies have examined potential contributors directly. Our objective was to identify specific factors that could contribute to seasonal variability using a large longitudinal dataset of HF ...
Prerna Gupta, Ellen Brinza, Prateeti Khazanie, Pamela N. Peterson, P Michael Ho, David P. Kao   +5 more
wiley   +1 more source

ICD-10 and the clinical features of depressions: data of the CIRCADIAN-I program

Неврология, нейропсихиатрия, психосоматика, 2011
The data of the CIRCADIAN-I trial suggest that depressions are unsatisfactorily diagnosed in psychiatric practice. Thus, some of the ICD-10 diagnoses used to denote depressive states (dysthymia, cyclothymia) are made extremely rarely.
O. V. Serdyuk, A. A. Ovchinnikov, N. A. Kutuzova, M. Yu. Drobizhev, K. Yu. Retyunsky   +4 more
doaj   +1 more source